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Concomitant Retinal Alterations in Neuronal Activity and TNFα Pathway Are Detectable during the Pre-Symptomatic Stage in a Mouse Model of Alzheimer’s Disease
The pre-symptomatic stage of Alzheimer’s disease (AD) is associated with increased amyloid-β (Aβ) precursor protein (APP) processing and Aβ accumulation in the retina and hippocampus. Because neuronal dysfunctions are among the earliest AD-related alterations, we asked whether they are already detec...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140134/ https://www.ncbi.nlm.nih.gov/pubmed/35626688 http://dx.doi.org/10.3390/cells11101650 |