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A Descriptive Review of the Impact of Patient Motion in Early Childhood Resting-State Functional Magnetic Resonance Imaging

Resting-state functional magnetic images (rs-fMRIs) can be used to map and delineate the brain activity occurring while the patient is in a task-free state. These resting-state activity networks can be informative when diagnosing various neurodevelopmental diseases, but only if the images are high q...

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Autores principales: Schabdach, Jenna, Ceschin, Rafael, Schmithorst, Vanessa, Tisdall, M. Dylan, Alexander-Bloch, Aaron, Panigrahy, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140169/
https://www.ncbi.nlm.nih.gov/pubmed/35626188
http://dx.doi.org/10.3390/diagnostics12051032
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author Schabdach, Jenna
Ceschin, Rafael
Schmithorst, Vanessa
Tisdall, M. Dylan
Alexander-Bloch, Aaron
Panigrahy, Ashok
author_facet Schabdach, Jenna
Ceschin, Rafael
Schmithorst, Vanessa
Tisdall, M. Dylan
Alexander-Bloch, Aaron
Panigrahy, Ashok
author_sort Schabdach, Jenna
collection PubMed
description Resting-state functional magnetic images (rs-fMRIs) can be used to map and delineate the brain activity occurring while the patient is in a task-free state. These resting-state activity networks can be informative when diagnosing various neurodevelopmental diseases, but only if the images are high quality. The quality of an rs-fMRI rapidly degrades when the patient moves during the scan. Herein, we describe how patient motion impacts an rs-fMRI on multiple levels. We begin with how the electromagnetic field and pulses of an MR scanner interact with a patient’s physiology, how movement affects the net signal acquired by the scanner, and how motion can be quantified from rs-fMRI. We then present methods for preventing motion through educational and behavioral interventions appropriate for different age groups, techniques for prospectively monitoring and correcting motion during the acquisition process, and pipelines for mitigating the effects of motion in existing scans.
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spelling pubmed-91401692022-05-28 A Descriptive Review of the Impact of Patient Motion in Early Childhood Resting-State Functional Magnetic Resonance Imaging Schabdach, Jenna Ceschin, Rafael Schmithorst, Vanessa Tisdall, M. Dylan Alexander-Bloch, Aaron Panigrahy, Ashok Diagnostics (Basel) Review Resting-state functional magnetic images (rs-fMRIs) can be used to map and delineate the brain activity occurring while the patient is in a task-free state. These resting-state activity networks can be informative when diagnosing various neurodevelopmental diseases, but only if the images are high quality. The quality of an rs-fMRI rapidly degrades when the patient moves during the scan. Herein, we describe how patient motion impacts an rs-fMRI on multiple levels. We begin with how the electromagnetic field and pulses of an MR scanner interact with a patient’s physiology, how movement affects the net signal acquired by the scanner, and how motion can be quantified from rs-fMRI. We then present methods for preventing motion through educational and behavioral interventions appropriate for different age groups, techniques for prospectively monitoring and correcting motion during the acquisition process, and pipelines for mitigating the effects of motion in existing scans. MDPI 2022-04-20 /pmc/articles/PMC9140169/ /pubmed/35626188 http://dx.doi.org/10.3390/diagnostics12051032 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Schabdach, Jenna
Ceschin, Rafael
Schmithorst, Vanessa
Tisdall, M. Dylan
Alexander-Bloch, Aaron
Panigrahy, Ashok
A Descriptive Review of the Impact of Patient Motion in Early Childhood Resting-State Functional Magnetic Resonance Imaging
title A Descriptive Review of the Impact of Patient Motion in Early Childhood Resting-State Functional Magnetic Resonance Imaging
title_full A Descriptive Review of the Impact of Patient Motion in Early Childhood Resting-State Functional Magnetic Resonance Imaging
title_fullStr A Descriptive Review of the Impact of Patient Motion in Early Childhood Resting-State Functional Magnetic Resonance Imaging
title_full_unstemmed A Descriptive Review of the Impact of Patient Motion in Early Childhood Resting-State Functional Magnetic Resonance Imaging
title_short A Descriptive Review of the Impact of Patient Motion in Early Childhood Resting-State Functional Magnetic Resonance Imaging
title_sort descriptive review of the impact of patient motion in early childhood resting-state functional magnetic resonance imaging
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140169/
https://www.ncbi.nlm.nih.gov/pubmed/35626188
http://dx.doi.org/10.3390/diagnostics12051032
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