Non-Mutated Nucleophosmin 1 Is Recognized by the CD8+ T Lymphocytes of an AML Patient after the Transplantation of Hematopoietic Stem Cells from an HLA-Haploidentical Donor

SIMPLE SUMMARY: Our study describes an AML patient whose leukemia cells carried the NPM1c(+) mutation, and who was the recipient of allogeneic HSCT from a haploidentical donor. The patient raised a robust allorestricted CD8(+) T cell response directed against the NPM1(wt) protein. Favourably, the re...

Descripción completa

Detalles Bibliográficos
Autores principales: Nemeckova, Sarka, Alexova-Zurkova, Kamila, Hainz, Petr, Krystofova, Jitka, Mackova, Jana, Roubalova, Katerina, Stastna-Markova, Marketa, Vrana, Milena, Vydra, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140185/
https://www.ncbi.nlm.nih.gov/pubmed/35621629
http://dx.doi.org/10.3390/curroncol29050239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140185/
https://www.ncbi.nlm.nih.gov/pubmed/35621629
http://dx.doi.org/10.3390/curroncol29050239

Ejemplares similares