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A novel bioassay to detect Nociceptin/Orphanin FQ release from single human polymorphonuclear cells

Nociceptin/Orphanin FQ (N/OFQ) is the endogenous opioid agonist for the N/OFQ receptor or NOP. This receptor system is involved in pain processing but also has a role in immune regulation. Indeed, polymorphonuclear cells (PMNs) express mRNA for N/OFQ precursor and are a potential source for circulat...

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Detalles Bibliográficos
Autores principales:	Bird, M. F., Hebbes, C. P., Scott, S. W. M., Willets, J., Thompson, J. P., Lambert, D. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140256/ https://www.ncbi.nlm.nih.gov/pubmed/35622823 http://dx.doi.org/10.1371/journal.pone.0268868

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