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Functional Dynamics of Substrate Recognition in TEM Beta-Lactamase

The beta-lactamase enzyme provides effective resistance to beta-lactam antibiotics due to substrate recognition controlled by point mutations. Recently, extended-spectrum and inhibitor-resistant mutants have become a global health problem. Here, the functional dynamics that control substrate recogni...

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Detalles Bibliográficos
Autores principales:	Avery, Chris, Baker, Lonnie, Jacobs, Donald J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140794/ https://www.ncbi.nlm.nih.gov/pubmed/35626612 http://dx.doi.org/10.3390/e24050729

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