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The requirement of phosphoenolpyruvate carboxykinase 1 for angiogenesis in vitro and in vivo

We here examined the potential biological function of phosphoenolpyruvate carboxykinase 1 (PCK1) in angiogenesis. shRNA- or CRISPR-Cas9–induced PCK1 depletion potently inhibited endothelial cell proliferation, migration, sprouting, and tube formation, whereas ectopic PCK1 overexpression exerted oppo...

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Detalles Bibliográficos
Autores principales:	Yao, Jin, Wu, Xin-yuan, Yu, Qing, Yang, Shuo-fei, Yuan, Jin, Zhang, Zhi-qing, Xue, Jin-song, Jiang, Qin, Chen, Min-bin, Xue, Guan-hua, Cao, Cong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140980/ https://www.ncbi.nlm.nih.gov/pubmed/35622925 http://dx.doi.org/10.1126/sciadv.abn6928

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