Efficient Simultaneous Introduction of Premature Stop Codons in Three Tumor Suppressor Genes in PFFs via a Cytosine Base Editor

Base editing is an efficient and precise gene-editing technique, by which a single base can be changed without introducing double-strand breaks, and it is currently widely used in studies of various species. In this study, we used hA3A-BE3-Y130F to simultaneously introduce premature stop codons (TAG...

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Detalles Bibliográficos
Autores principales: Jiang, Haoyun, Jing, Qiqi, Yang, Qiang, Qiao, Chuanmin, Liao, Yaya, Liu, Weiwei, Xing, Yuyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140995/
https://www.ncbi.nlm.nih.gov/pubmed/35627220
http://dx.doi.org/10.3390/genes13050835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140995/
https://www.ncbi.nlm.nih.gov/pubmed/35627220
http://dx.doi.org/10.3390/genes13050835

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