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Structural Abnormalities of the Optic Nerve and Retina in Huntington’s Disease Pre-Clinical and Clinical Settings

Huntington’s disease (HD) is a fatal neurodegenerative disorder caused by a polyglutamine expansion in the huntingtin protein. HD-related pathological remodelling has been reported in HD mouse models and HD carriers. In this study, we studied structural abnormalities in the optic nerve by employing...

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Detalles Bibliográficos
Autores principales: Mazur-Michałek, Iwona, Kowalska, Katarzyna, Zielonka, Daniel, Leśniczak-Staszak, Marta, Pietras, Paulina, Szaflarski, Witold, Isalan, Mark, Mielcarek, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141007/
https://www.ncbi.nlm.nih.gov/pubmed/35628260
http://dx.doi.org/10.3390/ijms23105450