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Clinical and Socio-Demographic Variables Associated with the Diagnosis of Long COVID Syndrome in Youth: A Population-Based Study

This study examines the demographic, clinical and socioeconomic factors associated with diagnosis of long COVID syndrome (LCS). Data of 20,601 COVID-19-positive children aged 5 to 18 years were collected between 2020 and 2021 in an Israeli database. Logistic regression analysis was used to evaluate...

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Autores principales: Merzon, Eugene, Weiss, Margaret, Krone, Beth, Cohen, Shira, Ilani, Gili, Vinker, Shlomo, Cohen-Golan, Avivit, Green, Ilan, Israel, Ariel, Schneider, Tzipporah, Ashkenazi, Shai, Weizman, Abraham, Manor, Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141083/
https://www.ncbi.nlm.nih.gov/pubmed/35627530
http://dx.doi.org/10.3390/ijerph19105993
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author Merzon, Eugene
Weiss, Margaret
Krone, Beth
Cohen, Shira
Ilani, Gili
Vinker, Shlomo
Cohen-Golan, Avivit
Green, Ilan
Israel, Ariel
Schneider, Tzipporah
Ashkenazi, Shai
Weizman, Abraham
Manor, Iris
author_facet Merzon, Eugene
Weiss, Margaret
Krone, Beth
Cohen, Shira
Ilani, Gili
Vinker, Shlomo
Cohen-Golan, Avivit
Green, Ilan
Israel, Ariel
Schneider, Tzipporah
Ashkenazi, Shai
Weizman, Abraham
Manor, Iris
author_sort Merzon, Eugene
collection PubMed
description This study examines the demographic, clinical and socioeconomic factors associated with diagnosis of long COVID syndrome (LCS). Data of 20,601 COVID-19-positive children aged 5 to 18 years were collected between 2020 and 2021 in an Israeli database. Logistic regression analysis was used to evaluate the adjusted odds ratio for the characteristics of the COVID-19 infection and pre-COVID-19 morbidities. Children with LCS were significantly more likely to have been severely symptomatic, required hospitalization, and experienced recurrent acute infection within 180 days. In addition, children with LCS were significantly more likely to have had ADHD, chronic urticaria, and allergic rhinitis. Diagnosis of LCS is significantly associated with pre-COVID-19 ADHD diagnosis, suggesting clinicians treating ADHD children who become infected with COVID-19 remain vigilant for the possibility of LCS. Although the risk of severe COVID-19 infection and LCS in children is low, further research on possible morbidity related to LCS in children is needed.
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spelling pubmed-91410832022-05-28 Clinical and Socio-Demographic Variables Associated with the Diagnosis of Long COVID Syndrome in Youth: A Population-Based Study Merzon, Eugene Weiss, Margaret Krone, Beth Cohen, Shira Ilani, Gili Vinker, Shlomo Cohen-Golan, Avivit Green, Ilan Israel, Ariel Schneider, Tzipporah Ashkenazi, Shai Weizman, Abraham Manor, Iris Int J Environ Res Public Health Article This study examines the demographic, clinical and socioeconomic factors associated with diagnosis of long COVID syndrome (LCS). Data of 20,601 COVID-19-positive children aged 5 to 18 years were collected between 2020 and 2021 in an Israeli database. Logistic regression analysis was used to evaluate the adjusted odds ratio for the characteristics of the COVID-19 infection and pre-COVID-19 morbidities. Children with LCS were significantly more likely to have been severely symptomatic, required hospitalization, and experienced recurrent acute infection within 180 days. In addition, children with LCS were significantly more likely to have had ADHD, chronic urticaria, and allergic rhinitis. Diagnosis of LCS is significantly associated with pre-COVID-19 ADHD diagnosis, suggesting clinicians treating ADHD children who become infected with COVID-19 remain vigilant for the possibility of LCS. Although the risk of severe COVID-19 infection and LCS in children is low, further research on possible morbidity related to LCS in children is needed. MDPI 2022-05-15 /pmc/articles/PMC9141083/ /pubmed/35627530 http://dx.doi.org/10.3390/ijerph19105993 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Merzon, Eugene
Weiss, Margaret
Krone, Beth
Cohen, Shira
Ilani, Gili
Vinker, Shlomo
Cohen-Golan, Avivit
Green, Ilan
Israel, Ariel
Schneider, Tzipporah
Ashkenazi, Shai
Weizman, Abraham
Manor, Iris
Clinical and Socio-Demographic Variables Associated with the Diagnosis of Long COVID Syndrome in Youth: A Population-Based Study
title Clinical and Socio-Demographic Variables Associated with the Diagnosis of Long COVID Syndrome in Youth: A Population-Based Study
title_full Clinical and Socio-Demographic Variables Associated with the Diagnosis of Long COVID Syndrome in Youth: A Population-Based Study
title_fullStr Clinical and Socio-Demographic Variables Associated with the Diagnosis of Long COVID Syndrome in Youth: A Population-Based Study
title_full_unstemmed Clinical and Socio-Demographic Variables Associated with the Diagnosis of Long COVID Syndrome in Youth: A Population-Based Study
title_short Clinical and Socio-Demographic Variables Associated with the Diagnosis of Long COVID Syndrome in Youth: A Population-Based Study
title_sort clinical and socio-demographic variables associated with the diagnosis of long covid syndrome in youth: a population-based study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141083/
https://www.ncbi.nlm.nih.gov/pubmed/35627530
http://dx.doi.org/10.3390/ijerph19105993
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