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Pyruvate Upregulates Hepatic FGF21 Expression by Activating PDE and Inhibiting cAMP–Epac–CREB Signaling Pathway

Fibroblast growth factor 21 (FGF21) functions as a polypeptide hormone to regulate glucose and lipid metabolism, and its expression is regulated by cellular metabolic stress. Pyruvate is an important intermediate metabolite that acts as a key hub for cellular fuel metabolism. However, the effect of...

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Detalles Bibliográficos
Autores principales:	Zhao, Yan-Yan, Zhang, Li-Jun, Liang, Xiang-Yan, Zhang, Xiao-Chun, Chang, Jin-Rui, Shi, Man, Liu, Huan, Zhou, Ying, Sun, Zhuo, Zhao, Yu-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141208/ https://www.ncbi.nlm.nih.gov/pubmed/35628302 http://dx.doi.org/10.3390/ijms23105490

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