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A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke

This study investigated the time-dependent characteristics of acupuncture and analyzed the association between acupuncture utilization and mortality rates, readmission rates, and complications among ischemic stroke patients. Data from the National Health Insurance Service-National Sample Cohort 2.0...

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Autores principales: Choi, Sung-Ryul, Kim, Eun-San, Jang, Bo-Hyoung, Jung, Boyoung, Ha, In-Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141209/
https://www.ncbi.nlm.nih.gov/pubmed/35627893
http://dx.doi.org/10.3390/healthcare10050756
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author Choi, Sung-Ryul
Kim, Eun-San
Jang, Bo-Hyoung
Jung, Boyoung
Ha, In-Hyuk
author_facet Choi, Sung-Ryul
Kim, Eun-San
Jang, Bo-Hyoung
Jung, Boyoung
Ha, In-Hyuk
author_sort Choi, Sung-Ryul
collection PubMed
description This study investigated the time-dependent characteristics of acupuncture and analyzed the association between acupuncture utilization and mortality rates, readmission rates, and complications among ischemic stroke patients. Data from the National Health Insurance Service-National Sample Cohort 2.0 from South Korea were used to track patients with subacute and chronic ischemic stroke, who had survived more than one month after onset, between 2010 and 2013. A total of 2299 patients were followed up until 2015. At baseline, the acupuncture group (n = 195) and the control group (n = 2104) had similar ages (acupuncture group: 69.0 ± 11.1 years; control group: 68.5 ± 11.8 years), but the acupuncture group had more comorbidities (Charlson comorbidity index; acupuncture group: 4.7 ± 2.1, control group: 4.3 ± 2.4). According to time-dependent Cox regression survival analysis, acupuncture treatment was associated with low hazard ratios (HR) for death (HR: 0.32; 95% confidence interval (CI): 0.18–0.60), fewer composite complications (HR: 0.34; 95% CI: 0.21–0.53), and reduced urinary tract infection (HR: 0.24; 95% CI: 0.11–0.54). Many acupuncture session sensitivity analyses were performed to assess the robustness using different criteria to define the acupuncture group, and the results were consistent with those of the main analysis. Therefore, acupuncture treatment might be associated with lower mortality rates and the prevention of complications after ischemic stroke.
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spelling pubmed-91412092022-05-28 A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke Choi, Sung-Ryul Kim, Eun-San Jang, Bo-Hyoung Jung, Boyoung Ha, In-Hyuk Healthcare (Basel) Article This study investigated the time-dependent characteristics of acupuncture and analyzed the association between acupuncture utilization and mortality rates, readmission rates, and complications among ischemic stroke patients. Data from the National Health Insurance Service-National Sample Cohort 2.0 from South Korea were used to track patients with subacute and chronic ischemic stroke, who had survived more than one month after onset, between 2010 and 2013. A total of 2299 patients were followed up until 2015. At baseline, the acupuncture group (n = 195) and the control group (n = 2104) had similar ages (acupuncture group: 69.0 ± 11.1 years; control group: 68.5 ± 11.8 years), but the acupuncture group had more comorbidities (Charlson comorbidity index; acupuncture group: 4.7 ± 2.1, control group: 4.3 ± 2.4). According to time-dependent Cox regression survival analysis, acupuncture treatment was associated with low hazard ratios (HR) for death (HR: 0.32; 95% confidence interval (CI): 0.18–0.60), fewer composite complications (HR: 0.34; 95% CI: 0.21–0.53), and reduced urinary tract infection (HR: 0.24; 95% CI: 0.11–0.54). Many acupuncture session sensitivity analyses were performed to assess the robustness using different criteria to define the acupuncture group, and the results were consistent with those of the main analysis. Therefore, acupuncture treatment might be associated with lower mortality rates and the prevention of complications after ischemic stroke. MDPI 2022-04-19 /pmc/articles/PMC9141209/ /pubmed/35627893 http://dx.doi.org/10.3390/healthcare10050756 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Choi, Sung-Ryul
Kim, Eun-San
Jang, Bo-Hyoung
Jung, Boyoung
Ha, In-Hyuk
A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke
title A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke
title_full A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke
title_fullStr A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke
title_full_unstemmed A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke
title_short A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke
title_sort time-dependent analysis of association between acupuncture utilization and the prognosis of ischemic stroke
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141209/
https://www.ncbi.nlm.nih.gov/pubmed/35627893
http://dx.doi.org/10.3390/healthcare10050756
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