Cargando…

Reversal of Right Ventricular Hypertrophy and Dysfunction by Prostacyclin in a Rat Model of Severe Pulmonary Arterial Hypertension

Prostacyclin analogs are among the most effective and widely used therapies for pulmonary arterial hypertension (PAH). However, it is unknown whether they also confer protection through right ventricle (RV) myocardio-specific mechanisms. Moreover, the use of prostacyclin analogs in severe models of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vanderpool, Rebecca R., Gorelova, Anastasia, Ma, Yiran, Alhamaydeh, Mohammad, Baust, Jeffrey, Shiva, Sruti, Tofovic, Stevan P., Hu, Jian, Nouraie, Seyed Mehdi, Gladwin, Mark T., Sharifi-Sanjani, Maryam, Al Ghouleh, Imad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141343/ https://www.ncbi.nlm.nih.gov/pubmed/35628236 http://dx.doi.org/10.3390/ijms23105426

Ejemplares similares

Yes-Associated Protein (Yap) Is Up-Regulated in Heart Failure and Promotes Cardiac Fibroblast Proliferation
por: Sharifi-Sanjani, Maryam, et al.
Publicado: (2021)

The Acute Effects of Prostacyclin on Right Ventricular Contractility and Pulmonary Artery Coupling
por: Vanderpool, Rebecca R., et al.
Publicado: (2023)

Experimental intravascular hemolysis induces hemodynamic and pathological pulmonary hypertension: association with accelerated purine metabolism
por: Bilan, Victor P., et al.
Publicado: (2018)

Recent advancements in pulmonary arterial hypertension and right heart failure research: overview of selected abstracts from ATS2020 and emerging COVID-19 research
por: Potus, Francois, et al.
Publicado: (2021)

Relaxin Inhibits Ventricular Arrhythmia and Asystole in Rats With Pulmonary Arterial Hypertension
por: Martin, Brian, et al.
Publicado: (2021)

New Tricks for an Old Drug: Prostacyclins and Right Ventricular Contractility in Pulmonary Arterial Hypertension
por: Wertheim, Bradley M.
Publicado: (2022)

A phenotype of increased sleepiness in a mouse model of pulmonary hypertension and right ventricular hypertrophy
por: Davis, Eric M., et al.
Publicado: (2018)

Correction: A phenotype of increased sleepiness in a mouse model of pulmonary hypertension and right ventricular hypertrophy
por: Davis, Eric M., et al.
Publicado: (2019)

Right ventricular function mirrors clinical improvement with use of prostacyclin analogues in pediatric pulmonary hypertension
por: Hopper, Rachel K., et al.
Publicado: (2018)

Right ventricular load and contractility in HIV-associated pulmonary hypertension
por: Rajaratnam, Arun, et al.
Publicado: (2021)

Estradiol Metabolism: Crossroads in Pulmonary Arterial Hypertension
por: Tofovic, Stevan P., et al.
Publicado: (2019)

PROSTACYCLIN IN HEALTH AND DISEASE
Publicado: (1983)

Prostacyclin: An Inflammatory Paradox
por: Stitham, Jeremiah, et al.
Publicado: (2011)

Prostacyclin Synthesis and Prostacyclin Receptor Expression in the Porcine Myometrium: Prostacyclin Potential to Regulate Fatty Acid Transporters, Cytokines and Contractility-Related Factors
por: Blitek, Agnieszka, et al.
Publicado: (2022)

Isolated Right Ventricular Apical Hypertrophy
por: Yamashita, Kentaro, et al.
Publicado: (2020)

Use of prostacyclin in pulmonary hypertension
por: Vicente, R, et al.
Publicado: (1998)

Role of prostacyclin in pulmonary hypertension
por: Mitchell, Jane A., et al.
Publicado: (2014)

Prostacyclin Regulation of Allergic Inflammation
por: Patel, Kunj, et al.
Publicado: (2022)

Right ventricular hypertrophy and hpertrabeculation misdiagnosed as a right ventricular mass on echocardiography
por: Fathala, Ahmed
Publicado: (2018)

DPP4 Inhibition, NPY(1-36), PYY(1-36), SDF-1α, and a Hypertensive Genetic Background Conspire to Augment Cell Proliferation and Collagen Production: Effects That Are Abolished by Low Concentrations of 2-Methoxyestradiol
por: Jackson, Edwin K., et al.
Publicado: (2020)

Growth Performance and Right Ventricular Hypertrophy Responses of Broiler Chickens to Guanidinoacetic Acid Supplementation under Hypobaric Hypoxia
por: Ahmadipour, Behnam, et al.
Publicado: (2018)

Variants in Human Prostacyclin Receptor Gene in Patients with Migraine Headache
por: Khorvash, Fariborz, et al.
Publicado: (2018)

Eicosanoids, prostacyclin and cyclooxygenase in the cardiovascular system
por: Mitchell, Jane A, et al.
Publicado: (2018)

Effect of p53 activation on experimental right ventricular hypertrophy
por: Veeroju, Swathi, et al.
Publicado: (2020)

Prostacyclin and thromboxane in benign and malignant breast tumours.
por: Laekeman, G. M., et al.
Publicado: (1986)

Selective inhibition of prostacyclin synthase activity by rofecoxib
por: Griffoni, Cristiana, et al.
Publicado: (2007)

The pulmonary and haematological toxicity of inhaled aerosolised prostacyclin
por: van Heerden, PV, et al.
Publicado: (1997)

“Yap”-ing about the Antifibrotic Benefits of Prostacyclin
por: Huang, Steven K.
Publicado: (2019)

Practical considerations for therapies targeting the prostacyclin pathway
por: Farber, Harrison W., et al.
Publicado: (2016)

Recurrent inhibition of mitochondrial complex III induces chronic pulmonary vasoconstriction and glycolytic switch in the rat lung
por: Rafikova, Olga, et al.
Publicado: (2018)

Role of Gender in Regulation of Redox Homeostasis in Pulmonary Arterial Hypertension
por: Rafikov, Ruslan, et al.
Publicado: (2019)

Focus on Early Events: Pathogenesis of Pulmonary Arterial Hypertension Development
por: Rafikova, Olga, et al.
Publicado: (2019)

Prostacyclins have no direct inotropic effect on isolated atrial strips from the normal and pressure-overloaded human right heart
por: Holmboe, Sarah, et al.
Publicado: (2017)

Carvedilol inhibits right ventricular hypertrophy induced by chronic hypobaric hypoxia
por: Tual, L, et al.
Publicado: (2006)

The role of prostacyclin in the interaction of endothelial cells and eosinophil granulocytes
por: Kónya, Viktória, et al.
Publicado: (2008)

Divergent roles of prostacyclin and PGE(2) in human tendinopathy
por: Bergqvist, Filip, et al.
Publicado: (2019)

Long‐Term Dipeptidyl Peptidase 4 Inhibition Worsens Hypertension and Renal and Cardiac Abnormalities in Obese Spontaneously Hypertensive Heart Failure Rats
por: Jackson, Edwin K., et al.
Publicado: (2021)

Cardiac CD47 Drives Left Ventricular Heart Failure Through Ca(2+)‐CaMKII‐Regulated Induction of HDAC3
por: Sharifi‐Sanjani, Maryam, et al.
Publicado: (2014)

Prostacyclin Analogue Beraprost Inhibits Cardiac Fibroblast Proliferation Depending on Prostacyclin Receptor Activation through a TGF β-Smad Signal Pathway
por: Chen, Yun, et al.
Publicado: (2014)

Senescence of bone marrow-derived mesenchymal stem cells from patients with idiopathic pulmonary fibrosis
por: Cárdenes, Nayra, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_pvbl1j5463kkaqa4976voovagn