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High Incidence Rate of SARS-CoV-2 Infection in Health Care Workers at a Dedicated COVID-19 Hospital: Experiences of the Pandemic from a Large Mexican Hospital

Health care workers (HCW) are at high risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The incidence of SARS-CoV-2 infection in HCW has been examined in cross-sectional studies by quantitative polymerase chain reaction (qPCR) tests, which may lead to underestimating ex...

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Autores principales: Bueno-Hernández, Nallely, Carrillo-Ruíz, José Damian, Méndez-García, Lucía A., Rizo-Téllez, Salma A., Viurcos-Sanabria, Rebeca, Santoyo-Chávez, Alisson, Márquez-Franco, René, Aguado-García, Alejandro, Baltazar-López, Neyla, Tomita-Cruz, Yoshio, Barrón, Eira Valeria, Sánchez, Ana Laura, Márquez, Edna, Fossion, Ruben, Rivera, Ana Leonor, Ruelas, Luis, Lecona, Octavio A., Martínez-Mekler, Gustavo, Müller, Markus, Arroyo-Valerio, América G., Escobedo, Galileo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141357/
https://www.ncbi.nlm.nih.gov/pubmed/35628032
http://dx.doi.org/10.3390/healthcare10050896
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author Bueno-Hernández, Nallely
Carrillo-Ruíz, José Damian
Méndez-García, Lucía A.
Rizo-Téllez, Salma A.
Viurcos-Sanabria, Rebeca
Santoyo-Chávez, Alisson
Márquez-Franco, René
Aguado-García, Alejandro
Baltazar-López, Neyla
Tomita-Cruz, Yoshio
Barrón, Eira Valeria
Sánchez, Ana Laura
Márquez, Edna
Fossion, Ruben
Rivera, Ana Leonor
Ruelas, Luis
Lecona, Octavio A.
Martínez-Mekler, Gustavo
Müller, Markus
Arroyo-Valerio, América G.
Escobedo, Galileo
author_facet Bueno-Hernández, Nallely
Carrillo-Ruíz, José Damian
Méndez-García, Lucía A.
Rizo-Téllez, Salma A.
Viurcos-Sanabria, Rebeca
Santoyo-Chávez, Alisson
Márquez-Franco, René
Aguado-García, Alejandro
Baltazar-López, Neyla
Tomita-Cruz, Yoshio
Barrón, Eira Valeria
Sánchez, Ana Laura
Márquez, Edna
Fossion, Ruben
Rivera, Ana Leonor
Ruelas, Luis
Lecona, Octavio A.
Martínez-Mekler, Gustavo
Müller, Markus
Arroyo-Valerio, América G.
Escobedo, Galileo
author_sort Bueno-Hernández, Nallely
collection PubMed
description Health care workers (HCW) are at high risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The incidence of SARS-CoV-2 infection in HCW has been examined in cross-sectional studies by quantitative polymerase chain reaction (qPCR) tests, which may lead to underestimating exact incidence rates. We thus investigated the incidence of SARS-CoV-2 infection in a group of HCW at a dedicated coronavirus disease 2019 (COVID-19) hospital in a six-month follow-up period. We conducted a prospective cohort study on 109 participants of both sexes working in areas of high, moderate, and low SARS-CoV-2 exposure. qPCR tests in nasopharyngeal swabs and anti-SARS-CoV-2 IgG serum antibodies were assessed at the beginning and six months later. Demographic, clinical, and laboratory parameters were analyzed according to IgG seropositivity by paired Student’s T-test or the chi-square test. The incidence rate of SARS-CoV-2 infection was considerably high in our cohort of HCW (58%), among whom 67% were asymptomatic carriers. No baseline risk factors contributed to the infection rate, including the workplace. It is still necessary to increase hospital safety procedures to prevent virus transmissibility from HCW to relatives and non-COVID-19 patients during the upcoming waves of contagion.
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spelling pubmed-91413572022-05-28 High Incidence Rate of SARS-CoV-2 Infection in Health Care Workers at a Dedicated COVID-19 Hospital: Experiences of the Pandemic from a Large Mexican Hospital Bueno-Hernández, Nallely Carrillo-Ruíz, José Damian Méndez-García, Lucía A. Rizo-Téllez, Salma A. Viurcos-Sanabria, Rebeca Santoyo-Chávez, Alisson Márquez-Franco, René Aguado-García, Alejandro Baltazar-López, Neyla Tomita-Cruz, Yoshio Barrón, Eira Valeria Sánchez, Ana Laura Márquez, Edna Fossion, Ruben Rivera, Ana Leonor Ruelas, Luis Lecona, Octavio A. Martínez-Mekler, Gustavo Müller, Markus Arroyo-Valerio, América G. Escobedo, Galileo Healthcare (Basel) Brief Report Health care workers (HCW) are at high risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The incidence of SARS-CoV-2 infection in HCW has been examined in cross-sectional studies by quantitative polymerase chain reaction (qPCR) tests, which may lead to underestimating exact incidence rates. We thus investigated the incidence of SARS-CoV-2 infection in a group of HCW at a dedicated coronavirus disease 2019 (COVID-19) hospital in a six-month follow-up period. We conducted a prospective cohort study on 109 participants of both sexes working in areas of high, moderate, and low SARS-CoV-2 exposure. qPCR tests in nasopharyngeal swabs and anti-SARS-CoV-2 IgG serum antibodies were assessed at the beginning and six months later. Demographic, clinical, and laboratory parameters were analyzed according to IgG seropositivity by paired Student’s T-test or the chi-square test. The incidence rate of SARS-CoV-2 infection was considerably high in our cohort of HCW (58%), among whom 67% were asymptomatic carriers. No baseline risk factors contributed to the infection rate, including the workplace. It is still necessary to increase hospital safety procedures to prevent virus transmissibility from HCW to relatives and non-COVID-19 patients during the upcoming waves of contagion. MDPI 2022-05-12 /pmc/articles/PMC9141357/ /pubmed/35628032 http://dx.doi.org/10.3390/healthcare10050896 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Bueno-Hernández, Nallely
Carrillo-Ruíz, José Damian
Méndez-García, Lucía A.
Rizo-Téllez, Salma A.
Viurcos-Sanabria, Rebeca
Santoyo-Chávez, Alisson
Márquez-Franco, René
Aguado-García, Alejandro
Baltazar-López, Neyla
Tomita-Cruz, Yoshio
Barrón, Eira Valeria
Sánchez, Ana Laura
Márquez, Edna
Fossion, Ruben
Rivera, Ana Leonor
Ruelas, Luis
Lecona, Octavio A.
Martínez-Mekler, Gustavo
Müller, Markus
Arroyo-Valerio, América G.
Escobedo, Galileo
High Incidence Rate of SARS-CoV-2 Infection in Health Care Workers at a Dedicated COVID-19 Hospital: Experiences of the Pandemic from a Large Mexican Hospital
title High Incidence Rate of SARS-CoV-2 Infection in Health Care Workers at a Dedicated COVID-19 Hospital: Experiences of the Pandemic from a Large Mexican Hospital
title_full High Incidence Rate of SARS-CoV-2 Infection in Health Care Workers at a Dedicated COVID-19 Hospital: Experiences of the Pandemic from a Large Mexican Hospital
title_fullStr High Incidence Rate of SARS-CoV-2 Infection in Health Care Workers at a Dedicated COVID-19 Hospital: Experiences of the Pandemic from a Large Mexican Hospital
title_full_unstemmed High Incidence Rate of SARS-CoV-2 Infection in Health Care Workers at a Dedicated COVID-19 Hospital: Experiences of the Pandemic from a Large Mexican Hospital
title_short High Incidence Rate of SARS-CoV-2 Infection in Health Care Workers at a Dedicated COVID-19 Hospital: Experiences of the Pandemic from a Large Mexican Hospital
title_sort high incidence rate of sars-cov-2 infection in health care workers at a dedicated covid-19 hospital: experiences of the pandemic from a large mexican hospital
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141357/
https://www.ncbi.nlm.nih.gov/pubmed/35628032
http://dx.doi.org/10.3390/healthcare10050896
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