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Ganglioside GM3 Synthase Deficiency in Mouse Models and Human Patients

Gangliosides (glycosphingolipids containing one or more sialic acids) are highly expressed in neural tissues in vertebrates, and four species (GM1a, GD1a, GD1b, GT1b) are predominant in mammalian brains. GM3 is the precursor of each of these four species and is the major ganglioside in many nonneura...

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Detalles Bibliográficos
Autores principales: Inamori, Kei-ichiro, Inokuchi, Jin-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141422/
https://www.ncbi.nlm.nih.gov/pubmed/35628171
http://dx.doi.org/10.3390/ijms23105368