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New Evidence on a Distinction between Aβ40 and Aβ42 Amyloids: Thioflavin T Binding Modes, Clustering Tendency, Degradation Resistance, and Cross-Seeding

The relative abundance of two main Abeta-peptide types with different lengths, Aβ40 and Aβ42, determines the severity of the Alzheimer’s disease progression. However, the factors responsible for different behavior patterns of these peptides in the amyloidogenesis process remain unknown. In this comp...

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Detalles Bibliográficos
Autores principales:	Sulatskaya, Anna I., Rychkov, Georgy N., Sulatsky, Maksim I., Mikhailova, Ekaterina V., Melnikova, Nadezhda M., Andozhskaya, Veronika S., Kuznetsova, Irina M., Turoverov, Konstantin K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141448/ https://www.ncbi.nlm.nih.gov/pubmed/35628325 http://dx.doi.org/10.3390/ijms23105513

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