Cargando…

New Evidence on a Distinction between Aβ40 and Aβ42 Amyloids: Thioflavin T Binding Modes, Clustering Tendency, Degradation Resistance, and Cross-Seeding

The relative abundance of two main Abeta-peptide types with different lengths, Aβ40 and Aβ42, determines the severity of the Alzheimer’s disease progression. However, the factors responsible for different behavior patterns of these peptides in the amyloidogenesis process remain unknown. In this comp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sulatskaya, Anna I., Rychkov, Georgy N., Sulatsky, Maksim I., Mikhailova, Ekaterina V., Melnikova, Nadezhda M., Andozhskaya, Veronika S., Kuznetsova, Irina M., Turoverov, Konstantin K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141448/ https://www.ncbi.nlm.nih.gov/pubmed/35628325 http://dx.doi.org/10.3390/ijms23105513

Ejemplares similares

Investigation of α-Synuclein Amyloid Fibrils Using the Fluorescent Probe Thioflavin T
por: Sulatskaya, Anna I., et al.
Publicado: (2018)

Analyzing Thioflavin T Binding to Amyloid Fibrils by an Equilibrium Microdialysis-Based Technique
por: Kuznetsova, Irina M., et al.
Publicado: (2012)

Structural Features of Amyloid Fibrils Formed from the Full-Length and Truncated Forms of Beta-2-Microglobulin Probed by Fluorescent Dye Thioflavin T
por: Sulatskaya, Anna I., et al.
Publicado: (2018)

Fluorescence Quantum Yield of Thioflavin T in Rigid Isotropic Solution and Incorporated into the Amyloid Fibrils
por: Sulatskaya, Anna I., et al.
Publicado: (2010)

Stoichiometry and Affinity of Thioflavin T Binding to Sup35p Amyloid Fibrils
por: Sulatskaya, Anna I., et al.
Publicado: (2016)

Trypsin Induced Degradation of Amyloid Fibrils
por: Stepanenko, Olga V., et al.
Publicado: (2021)

Amyloid fibrils degradation: the pathway to recovery or aggravation of the disease?
por: Sulatsky, Maksim I., et al.
Publicado: (2023)

Thioflavin T fluoresces as excimer in highly concentrated aqueous solutions and as monomer being incorporated in amyloid fibrils
por: Sulatskaya, Anna I., et al.
Publicado: (2017)

β-Barrels and Amyloids: Structural Transitions, Biological Functions, and Pathogenesis
por: Sulatskaya, Anna I., et al.
Publicado: (2021)

Amyloid Fibrils of Pisum sativum L. Vicilin Inhibit Pathological Aggregation of Mammalian Proteins
por: Sulatsky, Maksim I., et al.
Publicado: (2023)

Alpha-B-Crystallin Effect on Mature Amyloid Fibrils: Different Degradation Mechanisms and Changes in Cytotoxicity
por: Stepanenko, Olga V., et al.
Publicado: (2020)

Effect of the fluorescent probes ThT and ANS on the mature amyloid fibrils
por: Sulatsky, M. I., et al.
Publicado: (2020)

M60-like metalloprotease domain of the Escherichia coli YghJ protein forms amyloid fibrils
por: Belousov, Mikhail V., et al.
Publicado: (2018)

A novel study on amyloid β peptide 40, 42 and 40/42 ratio in Saudi autistics
por: Al- Ayadhi, Laila Y, et al.
Publicado: (2012)

Amyloid-β peptide 37, 38 and 40 individually and cooperatively inhibit amyloid-β 42 aggregation
por: Braun, Gabriel A., et al.
Publicado: (2022)

Is plasma amyloid-β 1–42/1–40 a better biomarker for Alzheimer’s disease than AβX–42/X–40?
por: Klafki, Hans-Wolfgang, et al.
Publicado: (2022)

X-ray diffraction and electron microscopy data for amyloid formation of Aβ40 and Aβ42
por: Selivanova, Olga M., et al.
Publicado: (2016)

Amyloid β-peptides 1–40 and 1–42 form oligomers with mixed β-sheets
por: Baldassarre, Maurizio, et al.
Publicado: (2017)

Cerebrospinal Fluid Aβ(42/40) Corresponds Better than Aβ(42) to Amyloid PET in Alzheimer’s Disease
por: Lewczuk, Piotr, et al.
Publicado: (2016)

P‐tau/Aβ42 and Aβ42/40 ratios in CSF are equally predictive of amyloid PET status
por: Campbell, Michelle R., et al.
Publicado: (2021)

Cathepsin D regulates cerebral Aβ42/40 ratios via differential degradation of Aβ42 and Aβ40
por: Suire, Caitlin N., et al.
Publicado: (2020)

Plasma amyloid β 42/40 ratios as biomarkers for amyloid β cerebral deposition in cognitively normal individuals
por: Fandos, Noelia, et al.
Publicado: (2017)

Diagnostic Utility of Selected Serum Dementia Biomarkers: Amyloid β-40, Amyloid β-42, Tau Protein, and YKL-40: A Review
por: Wilczyńska, Karolina, et al.
Publicado: (2020)

Predicting continuous amyloid PET values with CSF and plasma Aβ42/Aβ40
por: Wisch, Julie K., et al.
Publicado: (2023)

Reevaluation of ANS Binding to Human and Bovine Serum Albumins: Key Role of Equilibrium Microdialysis in Ligand – Receptor Binding Characterization
por: Kuznetsova, Irina M., et al.
Publicado: (2012)

CSF Aβ42 and Aβ42/Aβ40 Ratio in Alzheimer’s Disease and Frontotemporal Dementias
por: Constantinides, Vasilios C., et al.
Publicado: (2023)

Distributions of Aβ42 and Aβ42/40 in the Cerebrospinal Fluid in View of the Probability Theory
por: Lewczuk, Piotr, et al.
Publicado: (2021)

Inhalable Thioflavin S for the Detection of Amyloid Beta Deposits in the Retina
por: Barton, Shawn M., et al.
Publicado: (2021)

Aggregation States of Aβ(1–40), Aβ(1–42) and Aβp(3–42) Amyloid Beta Peptides: A SANS Study
por: Festa, Giulia, et al.
Publicado: (2019)

Fluorescence of Dyes in Solutions with High Absorbance. Inner Filter Effect Correction
por: Fonin, Alexander V., et al.
Publicado: (2014)

Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer’s Disease
por: Hansson, Oskar, et al.
Publicado: (2019)

Differentiating Aβ40 and Aβ42 in amyloid plaques with a small molecule fluorescence probe
por: Yang, Jing, et al.
Publicado: (2020)

Different associations between amyloid-βeta 42, amyloid-βeta 40, and amyloid-βeta 42/40 with soluble phosphorylated-tau and disease burden in Alzheimer’s disease: a cerebrospinal fluid and fluorodeoxyglucose-positron emission tomography study
por: Motta, Caterina, et al.
Publicado: (2023)

Two Novel Amyloid Proteins, RopA and RopB, from the Root Nodule Bacterium Rhizobium leguminosarum
por: Kosolapova, Anastasiia O., et al.
Publicado: (2019)

Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1–40 deposition underlies plaque polymorphism in progressing Alzheimer's disease pathology
por: Michno, Wojciech, et al.
Publicado: (2019)

CSF Aβ42/Aβ40 and Aβ42/Aβ38 ratios: better diagnostic markers of Alzheimer disease
por: Janelidze, Shorena, et al.
Publicado: (2016)

Exploring the occurrence of thioflavin-T-positive insulin amyloid aggregation intermediates
por: Ziaunys, Mantas, et al.
Publicado: (2021)

Plasma Amyloid-β Oligomerization Tendency Predicts Amyloid PET Positivity
por: Pyun, Jung-Min, et al.
Publicado: (2021)

Head-to-Head Comparison of 8 Plasma Amyloid-β 42/40 Assays in Alzheimer Disease
por: Janelidze, Shorena, et al.
Publicado: (2021)

Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40
por: Hu, Xiaoyan, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_m33d9vroc0sqguho3odi69ktvq