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Paroxysmal and Non-Paroxysmal Atrial Fibrillation in Middle Eastern Patients: Clinical Features and the Use of Medications. Analysis of the Jordan Atrial Fibrillation (JoFib) Study

(1) Background: Atrial fibrillation (AF) is the most common arrhythmia causing an increased risk of mortality and morbidity. It is classified into paroxysmal and non-paroxysmal AF depending on the duration and frequency of the episodes. (2) Aims: Our goal was to investigate and compare the clinical...

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Autores principales: Al-Makhamreh, Hanna, Alrabadi, Nasr, Haikal, Lubna, Krishan, Mohammad, Al-Badaineh, Noor, Odeh, Osama, Barqawi, Tawfiq, Nawaiseh, Mohammed, Shaban, Ala, Abdin, Basil, Khamies, Lama, Hammoudeh, Ayman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141457/
https://www.ncbi.nlm.nih.gov/pubmed/35627709
http://dx.doi.org/10.3390/ijerph19106173
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author Al-Makhamreh, Hanna
Alrabadi, Nasr
Haikal, Lubna
Krishan, Mohammad
Al-Badaineh, Noor
Odeh, Osama
Barqawi, Tawfiq
Nawaiseh, Mohammed
Shaban, Ala
Abdin, Basil
Khamies, Lama
Hammoudeh, Ayman
author_facet Al-Makhamreh, Hanna
Alrabadi, Nasr
Haikal, Lubna
Krishan, Mohammad
Al-Badaineh, Noor
Odeh, Osama
Barqawi, Tawfiq
Nawaiseh, Mohammed
Shaban, Ala
Abdin, Basil
Khamies, Lama
Hammoudeh, Ayman
author_sort Al-Makhamreh, Hanna
collection PubMed
description (1) Background: Atrial fibrillation (AF) is the most common arrhythmia causing an increased risk of mortality and morbidity. It is classified into paroxysmal and non-paroxysmal AF depending on the duration and frequency of the episodes. (2) Aims: Our goal was to investigate and compare the clinical profiles, risk of co-morbidities, the use of oral anticoagulation, and outcomes of patients with paroxysmal and non-paroxysmal AF in inpatient and outpatient settings. (3) Methods: Data were extracted from 28 different hospitals and centers in Jordan with a total of 2160 patients enrolled in the study using an observational non-interventional study model. The clinical features and the use of oral anticoagulants were compared in patients with paroxysmal and non-paroxysmal AF. (4) Results: Paroxysmal AF was documented in 35.6% (769) of the patients and non-paroxysmal types in 63.9% (1380); in addition, the type of AF was unknown in 11 (0.5%) patients. Our results showed that non-paroxysmal AF patients tend to be older with more co-morbidities and higher CHA2DS2-VASC and HAS-BLED scores. They also have higher rates of hypertension and diabetes. Anticoagulant, antiarrhythmic, and diuretic agents, overall, were used more in non-paroxysmal AF than paroxysmal AF. Hospital admissions were also more frequent in non-paroxysmal AF due to various factors, some of which are heart failure, bleeding risk, and COPD. (5) Conclusions: Non-paroxysmal AF is more common among Jordanian AF patients. The prevalence of comorbidities and the use of different types of therapies, especially anticoagulants, were higher in these patients.
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spelling pubmed-91414572022-05-28 Paroxysmal and Non-Paroxysmal Atrial Fibrillation in Middle Eastern Patients: Clinical Features and the Use of Medications. Analysis of the Jordan Atrial Fibrillation (JoFib) Study Al-Makhamreh, Hanna Alrabadi, Nasr Haikal, Lubna Krishan, Mohammad Al-Badaineh, Noor Odeh, Osama Barqawi, Tawfiq Nawaiseh, Mohammed Shaban, Ala Abdin, Basil Khamies, Lama Hammoudeh, Ayman Int J Environ Res Public Health Article (1) Background: Atrial fibrillation (AF) is the most common arrhythmia causing an increased risk of mortality and morbidity. It is classified into paroxysmal and non-paroxysmal AF depending on the duration and frequency of the episodes. (2) Aims: Our goal was to investigate and compare the clinical profiles, risk of co-morbidities, the use of oral anticoagulation, and outcomes of patients with paroxysmal and non-paroxysmal AF in inpatient and outpatient settings. (3) Methods: Data were extracted from 28 different hospitals and centers in Jordan with a total of 2160 patients enrolled in the study using an observational non-interventional study model. The clinical features and the use of oral anticoagulants were compared in patients with paroxysmal and non-paroxysmal AF. (4) Results: Paroxysmal AF was documented in 35.6% (769) of the patients and non-paroxysmal types in 63.9% (1380); in addition, the type of AF was unknown in 11 (0.5%) patients. Our results showed that non-paroxysmal AF patients tend to be older with more co-morbidities and higher CHA2DS2-VASC and HAS-BLED scores. They also have higher rates of hypertension and diabetes. Anticoagulant, antiarrhythmic, and diuretic agents, overall, were used more in non-paroxysmal AF than paroxysmal AF. Hospital admissions were also more frequent in non-paroxysmal AF due to various factors, some of which are heart failure, bleeding risk, and COPD. (5) Conclusions: Non-paroxysmal AF is more common among Jordanian AF patients. The prevalence of comorbidities and the use of different types of therapies, especially anticoagulants, were higher in these patients. MDPI 2022-05-19 /pmc/articles/PMC9141457/ /pubmed/35627709 http://dx.doi.org/10.3390/ijerph19106173 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Al-Makhamreh, Hanna
Alrabadi, Nasr
Haikal, Lubna
Krishan, Mohammad
Al-Badaineh, Noor
Odeh, Osama
Barqawi, Tawfiq
Nawaiseh, Mohammed
Shaban, Ala
Abdin, Basil
Khamies, Lama
Hammoudeh, Ayman
Paroxysmal and Non-Paroxysmal Atrial Fibrillation in Middle Eastern Patients: Clinical Features and the Use of Medications. Analysis of the Jordan Atrial Fibrillation (JoFib) Study
title Paroxysmal and Non-Paroxysmal Atrial Fibrillation in Middle Eastern Patients: Clinical Features and the Use of Medications. Analysis of the Jordan Atrial Fibrillation (JoFib) Study
title_full Paroxysmal and Non-Paroxysmal Atrial Fibrillation in Middle Eastern Patients: Clinical Features and the Use of Medications. Analysis of the Jordan Atrial Fibrillation (JoFib) Study
title_fullStr Paroxysmal and Non-Paroxysmal Atrial Fibrillation in Middle Eastern Patients: Clinical Features and the Use of Medications. Analysis of the Jordan Atrial Fibrillation (JoFib) Study
title_full_unstemmed Paroxysmal and Non-Paroxysmal Atrial Fibrillation in Middle Eastern Patients: Clinical Features and the Use of Medications. Analysis of the Jordan Atrial Fibrillation (JoFib) Study
title_short Paroxysmal and Non-Paroxysmal Atrial Fibrillation in Middle Eastern Patients: Clinical Features and the Use of Medications. Analysis of the Jordan Atrial Fibrillation (JoFib) Study
title_sort paroxysmal and non-paroxysmal atrial fibrillation in middle eastern patients: clinical features and the use of medications. analysis of the jordan atrial fibrillation (jofib) study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141457/
https://www.ncbi.nlm.nih.gov/pubmed/35627709
http://dx.doi.org/10.3390/ijerph19106173
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