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Cdh1 Deficiency Sensitizes TNBC Cells to PARP Inhibitors

Triple-negative breast cancer (TNBC) is a type of breast tumor that currently lacks options for targeted therapy. Tremendous effort has been made to identify treatment targets for TNBC. Here, we report that the expression level of anaphase promoting complex (APC) coactivator Cdh1 in TNBC is elevated...

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Detalles Bibliográficos
Autores principales: Li, Junjun, Lan, Mengjiao, Peng, Jin, Xiong, Qunli, Xu, Yongfeng, Yang, Yang, Zhou, Ying, Liu, Jinlu, Zeng, Zhu, Yang, Xiaojuan, Zhang, Zhiwei, Zhang, Pumin, Zhu, Qing, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141497/
https://www.ncbi.nlm.nih.gov/pubmed/35627188
http://dx.doi.org/10.3390/genes13050803