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Insights into the Mechanism of Human Deiodinase 1

The three isoenzymes of iodothyronine deiodinases (DIO1-3) are membrane-anchored homo-dimeric selenoproteins which share the thioredoxin-fold structure. Several questions regarding their catalytic mechanisms still remain open. Here, we addressed the roles of several cysteines which are conserved amo...

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Detalles Bibliográficos
Autores principales: Rodriguez-Ruiz, Alfonso, Braun, Doreen, Pflug, Simon, Brol, Alexander, Sylvester, Marc, Steegborn, Clemens, Schweizer, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141512/
https://www.ncbi.nlm.nih.gov/pubmed/35628173
http://dx.doi.org/10.3390/ijms23105361

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