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Insights into the Mechanism of Human Deiodinase 1
The three isoenzymes of iodothyronine deiodinases (DIO1-3) are membrane-anchored homo-dimeric selenoproteins which share the thioredoxin-fold structure. Several questions regarding their catalytic mechanisms still remain open. Here, we addressed the roles of several cysteines which are conserved amo...
Autores principales: | Rodriguez-Ruiz, Alfonso, Braun, Doreen, Pflug, Simon, Brol, Alexander, Sylvester, Marc, Steegborn, Clemens, Schweizer, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141512/ https://www.ncbi.nlm.nih.gov/pubmed/35628173 http://dx.doi.org/10.3390/ijms23105361 |
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