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Utility of Next-Generation Sequencing in the Reconstruction of Clonal Architecture in a Patient with an EGFR Mutated Advanced Non-Small Cell Lung Cancer: A Case Report

EGFR tyrosine kinase inhibitors (EGFR-TKIs) have revolutionized the treatment of non-small cell lung cancer (NSCLC) patients with activating EGFR mutations. However, targeted therapies impose a strong selective pressure against the coexisting tumor populations that lead to the emergence of resistant...

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Detalles Bibliográficos
Autores principales:	Simarro, Javier, Pérez-Simó, Gema, Mancheño, Nuria, Muñoz-Núñez, Carlos Francisco, Cases, Enrique, Juan, Óscar, Palanca, Sarai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141594/ https://www.ncbi.nlm.nih.gov/pubmed/35626421 http://dx.doi.org/10.3390/diagnostics12051266

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