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One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking
In this study, a series of gelatin/silver nanoparticles (AgNPs) composite hydrogels are prepared for the first time through the facile in situ formation of AgNPs. AgNPs, which are formed by reducing Ag(+) using dopamine-conjugated gelatins. These can simultaneously crosslink gelatin molecules, thus...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141602/ https://www.ncbi.nlm.nih.gov/pubmed/35621554 http://dx.doi.org/10.3390/gels8050256 |
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author | Li, Yi Xiao, Yunchao Xi, Man Li, Guibin Jiang, Yang |
author_facet | Li, Yi Xiao, Yunchao Xi, Man Li, Guibin Jiang, Yang |
author_sort | Li, Yi |
collection | PubMed |
description | In this study, a series of gelatin/silver nanoparticles (AgNPs) composite hydrogels are prepared for the first time through the facile in situ formation of AgNPs. AgNPs, which are formed by reducing Ag(+) using dopamine-conjugated gelatins. These can simultaneously crosslink gelatin molecules, thus generating three-dimentional and porous hydrogels. The gelation time and pore sizes of these composite hydrogels can be controlled by controlling the feeding concentration of AgNO(3) and weight content of gelatin in water, respectively. The feeding concentration of AgNO(3) also has an effect on the equilibrium swelling ratio of the hydrogels. Moreover, these composite hydrogels, with a controllable gelation time and in situ forming ability, exhibit good adhesive properties and can be used as drug-release depots. |
format | Online Article Text |
id | pubmed-9141602 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91416022022-05-28 One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking Li, Yi Xiao, Yunchao Xi, Man Li, Guibin Jiang, Yang Gels Article In this study, a series of gelatin/silver nanoparticles (AgNPs) composite hydrogels are prepared for the first time through the facile in situ formation of AgNPs. AgNPs, which are formed by reducing Ag(+) using dopamine-conjugated gelatins. These can simultaneously crosslink gelatin molecules, thus generating three-dimentional and porous hydrogels. The gelation time and pore sizes of these composite hydrogels can be controlled by controlling the feeding concentration of AgNO(3) and weight content of gelatin in water, respectively. The feeding concentration of AgNO(3) also has an effect on the equilibrium swelling ratio of the hydrogels. Moreover, these composite hydrogels, with a controllable gelation time and in situ forming ability, exhibit good adhesive properties and can be used as drug-release depots. MDPI 2022-04-21 /pmc/articles/PMC9141602/ /pubmed/35621554 http://dx.doi.org/10.3390/gels8050256 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Li, Yi Xiao, Yunchao Xi, Man Li, Guibin Jiang, Yang One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking |
title | One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking |
title_full | One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking |
title_fullStr | One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking |
title_full_unstemmed | One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking |
title_short | One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking |
title_sort | one-step preparation of adhesive composite hydrogels through fast and simultaneous in situ formation of silver nanoparticles and crosslinking |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141602/ https://www.ncbi.nlm.nih.gov/pubmed/35621554 http://dx.doi.org/10.3390/gels8050256 |
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