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One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking

In this study, a series of gelatin/silver nanoparticles (AgNPs) composite hydrogels are prepared for the first time through the facile in situ formation of AgNPs. AgNPs, which are formed by reducing Ag(+) using dopamine-conjugated gelatins. These can simultaneously crosslink gelatin molecules, thus...

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Detalles Bibliográficos
Autores principales: Li, Yi, Xiao, Yunchao, Xi, Man, Li, Guibin, Jiang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141602/
https://www.ncbi.nlm.nih.gov/pubmed/35621554
http://dx.doi.org/10.3390/gels8050256
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author Li, Yi
Xiao, Yunchao
Xi, Man
Li, Guibin
Jiang, Yang
author_facet Li, Yi
Xiao, Yunchao
Xi, Man
Li, Guibin
Jiang, Yang
author_sort Li, Yi
collection PubMed
description In this study, a series of gelatin/silver nanoparticles (AgNPs) composite hydrogels are prepared for the first time through the facile in situ formation of AgNPs. AgNPs, which are formed by reducing Ag(+) using dopamine-conjugated gelatins. These can simultaneously crosslink gelatin molecules, thus generating three-dimentional and porous hydrogels. The gelation time and pore sizes of these composite hydrogels can be controlled by controlling the feeding concentration of AgNO(3) and weight content of gelatin in water, respectively. The feeding concentration of AgNO(3) also has an effect on the equilibrium swelling ratio of the hydrogels. Moreover, these composite hydrogels, with a controllable gelation time and in situ forming ability, exhibit good adhesive properties and can be used as drug-release depots.
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spelling pubmed-91416022022-05-28 One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking Li, Yi Xiao, Yunchao Xi, Man Li, Guibin Jiang, Yang Gels Article In this study, a series of gelatin/silver nanoparticles (AgNPs) composite hydrogels are prepared for the first time through the facile in situ formation of AgNPs. AgNPs, which are formed by reducing Ag(+) using dopamine-conjugated gelatins. These can simultaneously crosslink gelatin molecules, thus generating three-dimentional and porous hydrogels. The gelation time and pore sizes of these composite hydrogels can be controlled by controlling the feeding concentration of AgNO(3) and weight content of gelatin in water, respectively. The feeding concentration of AgNO(3) also has an effect on the equilibrium swelling ratio of the hydrogels. Moreover, these composite hydrogels, with a controllable gelation time and in situ forming ability, exhibit good adhesive properties and can be used as drug-release depots. MDPI 2022-04-21 /pmc/articles/PMC9141602/ /pubmed/35621554 http://dx.doi.org/10.3390/gels8050256 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Li, Yi
Xiao, Yunchao
Xi, Man
Li, Guibin
Jiang, Yang
One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking
title One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking
title_full One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking
title_fullStr One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking
title_full_unstemmed One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking
title_short One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking
title_sort one-step preparation of adhesive composite hydrogels through fast and simultaneous in situ formation of silver nanoparticles and crosslinking
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141602/
https://www.ncbi.nlm.nih.gov/pubmed/35621554
http://dx.doi.org/10.3390/gels8050256
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