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Dopamine Photochemical Behaviour under UV Irradiation
To understand the photochemical behaviour of the polydopamine polymer in detail, one would also need to know the behaviour of its building blocks. The electronic absorption, as well as the fluorescence emission and excitation spectra of the dopamine were experimentally and theoretically investigated...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141693/ https://www.ncbi.nlm.nih.gov/pubmed/35628293 http://dx.doi.org/10.3390/ijms23105483 |
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author | Falamaş, Alexandra Petran, Anca Hada, Alexandru-Milentie Bende, Attila |
author_facet | Falamaş, Alexandra Petran, Anca Hada, Alexandru-Milentie Bende, Attila |
author_sort | Falamaş, Alexandra |
collection | PubMed |
description | To understand the photochemical behaviour of the polydopamine polymer in detail, one would also need to know the behaviour of its building blocks. The electronic absorption, as well as the fluorescence emission and excitation spectra of the dopamine were experimentally and theoretically investigated considering time-resolved fluorescence spectroscopy and first-principles quantum theory methods. The shape of the experimental absorption spectra obtained for different dopamine species with standard, zwitterionic, protonated, and deprotonated geometries was interpreted by considering the advanced equation-of-motion coupled-cluster theory of DLPNO-STEOM. Dynamical properties such as fluorescence lifetimes or quantum yield were also experimentally investigated and compared with theoretically predicted transition rates based on Fermi’s Golden Rule-like equation. The results show that the photochemical behaviour of dopamine is strongly dependent on the concentration of dopamine, whereas in the case of a high concentration, the zwitterionic form significantly affects the shape of the spectrum. On the other hand, the solvent pH is also a determining factor for the absorption, but especially for the fluorescence spectrum, where at lower pH (5.5), the protonated and, at higher pH (8.0), the deprotonated forms influence the shape of the spectra. Quantum yield measurements showed that, besides the radiative deactivation mechanism characterized by a relatively small QY value, non-radiative deactivation channels are very important in the relaxation process of the electronic excited states of different dopamine species. |
format | Online Article Text |
id | pubmed-9141693 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91416932022-05-28 Dopamine Photochemical Behaviour under UV Irradiation Falamaş, Alexandra Petran, Anca Hada, Alexandru-Milentie Bende, Attila Int J Mol Sci Article To understand the photochemical behaviour of the polydopamine polymer in detail, one would also need to know the behaviour of its building blocks. The electronic absorption, as well as the fluorescence emission and excitation spectra of the dopamine were experimentally and theoretically investigated considering time-resolved fluorescence spectroscopy and first-principles quantum theory methods. The shape of the experimental absorption spectra obtained for different dopamine species with standard, zwitterionic, protonated, and deprotonated geometries was interpreted by considering the advanced equation-of-motion coupled-cluster theory of DLPNO-STEOM. Dynamical properties such as fluorescence lifetimes or quantum yield were also experimentally investigated and compared with theoretically predicted transition rates based on Fermi’s Golden Rule-like equation. The results show that the photochemical behaviour of dopamine is strongly dependent on the concentration of dopamine, whereas in the case of a high concentration, the zwitterionic form significantly affects the shape of the spectrum. On the other hand, the solvent pH is also a determining factor for the absorption, but especially for the fluorescence spectrum, where at lower pH (5.5), the protonated and, at higher pH (8.0), the deprotonated forms influence the shape of the spectra. Quantum yield measurements showed that, besides the radiative deactivation mechanism characterized by a relatively small QY value, non-radiative deactivation channels are very important in the relaxation process of the electronic excited states of different dopamine species. MDPI 2022-05-13 /pmc/articles/PMC9141693/ /pubmed/35628293 http://dx.doi.org/10.3390/ijms23105483 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Falamaş, Alexandra Petran, Anca Hada, Alexandru-Milentie Bende, Attila Dopamine Photochemical Behaviour under UV Irradiation |
title | Dopamine Photochemical Behaviour under UV Irradiation |
title_full | Dopamine Photochemical Behaviour under UV Irradiation |
title_fullStr | Dopamine Photochemical Behaviour under UV Irradiation |
title_full_unstemmed | Dopamine Photochemical Behaviour under UV Irradiation |
title_short | Dopamine Photochemical Behaviour under UV Irradiation |
title_sort | dopamine photochemical behaviour under uv irradiation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141693/ https://www.ncbi.nlm.nih.gov/pubmed/35628293 http://dx.doi.org/10.3390/ijms23105483 |
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