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Glucocorticoid Receptor β Overexpression Has Agonist-Independent Insulin-Mimetic Effects on HepG2 Glucose Metabolism

Glucocorticoids (GC) are steroids hormones that drive circulating glucose availability through gluconeogenesis in the liver. However, alternative splicing of the GR mRNA produces two isoforms, termed GRα and GRβ. GRα is the classic receptor that binds to GCs and mediates the most described actions o...

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Detalles Bibliográficos
Autores principales: Sepúlveda-Quiñenao, Claudia, Rodriguez, Juan M., Díaz-Castro, Francisco, del Campo, Andrea, Bravo-Sagua, Roberto, Troncoso, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141770/
https://www.ncbi.nlm.nih.gov/pubmed/35628392
http://dx.doi.org/10.3390/ijms23105582