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Glucocorticoid Receptor β Overexpression Has Agonist-Independent Insulin-Mimetic Effects on HepG2 Glucose Metabolism
Glucocorticoids (GC) are steroids hormones that drive circulating glucose availability through gluconeogenesis in the liver. However, alternative splicing of the GR mRNA produces two isoforms, termed GRα and GRβ. GRα is the classic receptor that binds to GCs and mediates the most described actions o...
Autores principales: | Sepúlveda-Quiñenao, Claudia, Rodriguez, Juan M., Díaz-Castro, Francisco, del Campo, Andrea, Bravo-Sagua, Roberto, Troncoso, Rodrigo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141770/ https://www.ncbi.nlm.nih.gov/pubmed/35628392 http://dx.doi.org/10.3390/ijms23105582 |
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