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The Deubiquitinase USP39 Promotes Esophageal Squamous Cell Carcinoma Malignancy as a Splicing Factor

Esophageal squamous cell carcinoma (ESCC) is an aggressive epithelial malignancy and the underlying molecular mechanisms remain elusive. Here, we identify that the ubiquitin-specific protease 39 (USP39) drives cell growth and chemoresistance by functional screening in ESCC, and that high expression...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaolin, Ma, Jianlin, Lu, Minyi, Liu, Zhihua, Sun, Yongkun, Chen, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141838/
https://www.ncbi.nlm.nih.gov/pubmed/35627203
http://dx.doi.org/10.3390/genes13050819