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Secreted HSP90α-LRP1 Signaling Promotes Tumor Metastasis and Chemoresistance in Pancreatic Cancer

The extracellular heat shock protein 90α (eHSP90α) has been reported to promote cancer cell motility. However, whether pancreatic cancer (PC) cells expressed membrane-bound or secreted HSP90α, as well as its underlying mechanism for PC progression, were still unclear. Our study demonstrated that the...

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Detalles Bibliográficos
Autores principales: Xue, Nina, Du, Tingting, Lai, Fangfang, Jin, Jing, Ji, Ming, Chen, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141888/
https://www.ncbi.nlm.nih.gov/pubmed/35628341
http://dx.doi.org/10.3390/ijms23105532