Laboratory Diagnosis for SARS-CoV-2 Infection

The optimal diagnostic test for SARS-CoV-2 infection should be selected based on a patient’s clinical syndrome and presentation in relation to symptom onset. Molecular testing, most often reverse-transcriptase polymerase chain reaction, offers the highest sensitivity and specificity during acute inf...

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Detalles Bibliográficos
Autores principales: Christensen, Bianca B., Azar, Marwan M., Turbett, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141924/
https://www.ncbi.nlm.nih.gov/pubmed/35636903
http://dx.doi.org/10.1016/j.idc.2022.02.002
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author Christensen, Bianca B.
Azar, Marwan M.
Turbett, Sarah E.
author_facet Christensen, Bianca B.
Azar, Marwan M.
Turbett, Sarah E.
author_sort Christensen, Bianca B.
collection PubMed
description The optimal diagnostic test for SARS-CoV-2 infection should be selected based on a patient’s clinical syndrome and presentation in relation to symptom onset. Molecular testing, most often reverse-transcriptase polymerase chain reaction, offers the highest sensitivity and specificity during acute infection, whereas antigen testing can also be useful for acute diagnosis when rapid turnaround of results is necessary or if molecular testing is unavailable. Serologic testing is often reserved for identifying individuals with prior or late COVID-19 infection.
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spelling pubmed-91419242022-05-31 Laboratory Diagnosis for SARS-CoV-2 Infection Christensen, Bianca B. Azar, Marwan M. Turbett, Sarah E. Infect Dis Clin North Am Article The optimal diagnostic test for SARS-CoV-2 infection should be selected based on a patient’s clinical syndrome and presentation in relation to symptom onset. Molecular testing, most often reverse-transcriptase polymerase chain reaction, offers the highest sensitivity and specificity during acute infection, whereas antigen testing can also be useful for acute diagnosis when rapid turnaround of results is necessary or if molecular testing is unavailable. Serologic testing is often reserved for identifying individuals with prior or late COVID-19 infection. Elsevier Inc. 2022-06 2022-05-27 /pmc/articles/PMC9141924/ /pubmed/35636903 http://dx.doi.org/10.1016/j.idc.2022.02.002 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Christensen, Bianca B.
Azar, Marwan M.
Turbett, Sarah E.
Laboratory Diagnosis for SARS-CoV-2 Infection
title Laboratory Diagnosis for SARS-CoV-2 Infection
title_full Laboratory Diagnosis for SARS-CoV-2 Infection
title_fullStr Laboratory Diagnosis for SARS-CoV-2 Infection
title_full_unstemmed Laboratory Diagnosis for SARS-CoV-2 Infection
title_short Laboratory Diagnosis for SARS-CoV-2 Infection
title_sort laboratory diagnosis for sars-cov-2 infection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141924/
https://www.ncbi.nlm.nih.gov/pubmed/35636903
http://dx.doi.org/10.1016/j.idc.2022.02.002
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