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Transgenic Mouse Models of Alzheimer’s Disease: An Integrative Analysis

Alzheimer’s disease (AD) constitutes the most prominent form of dementia among elderly individuals worldwide. Disease modeling using murine transgenic mice was first initiated thanks to the discovery of heritable mutations in amyloid precursor protein (APP) and presenilins (PS) genes. However, due t...

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Detalles Bibliográficos
Autores principales: Sanchez-Varo, Raquel, Mejias-Ortega, Marina, Fernandez-Valenzuela, Juan Jose, Nuñez-Diaz, Cristina, Caceres-Palomo, Laura, Vegas-Gomez, Laura, Sanchez-Mejias, Elisabeth, Trujillo-Estrada, Laura, Garcia-Leon, Juan Antonio, Moreno-Gonzalez, Ines, Vizuete, Marisa, Vitorica, Javier, Baglietto-Vargas, David, Gutierrez, Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142061/
https://www.ncbi.nlm.nih.gov/pubmed/35628216
http://dx.doi.org/10.3390/ijms23105404