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Chaos in Cancer Tumor Growth Model with Commensurate and Incommensurate Fractional-Order Derivatives

Analyzing the dynamics of tumor-immune systems can play an important role in the fight against cancer, since it can foster the development of more effective medical treatments. This paper was aimed at making a contribution to the study of tumor-immune dynamics by presenting a new model of cancer gro...

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Autores principales: Debbouche, Nadjette, Ouannas, Adel, Grassi, Giuseppe, Al-Hussein, Abdul-Basset A., Tahir, Fadhil Rahma, Saad, Khaled M., Jahanshahi, Hadi, Aly, Ayman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142312/
https://www.ncbi.nlm.nih.gov/pubmed/35633919
http://dx.doi.org/10.1155/2022/5227503
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author Debbouche, Nadjette
Ouannas, Adel
Grassi, Giuseppe
Al-Hussein, Abdul-Basset A.
Tahir, Fadhil Rahma
Saad, Khaled M.
Jahanshahi, Hadi
Aly, Ayman A.
author_facet Debbouche, Nadjette
Ouannas, Adel
Grassi, Giuseppe
Al-Hussein, Abdul-Basset A.
Tahir, Fadhil Rahma
Saad, Khaled M.
Jahanshahi, Hadi
Aly, Ayman A.
author_sort Debbouche, Nadjette
collection PubMed
description Analyzing the dynamics of tumor-immune systems can play an important role in the fight against cancer, since it can foster the development of more effective medical treatments. This paper was aimed at making a contribution to the study of tumor-immune dynamics by presenting a new model of cancer growth based on fractional-order differential equations. By investigating the system dynamics, the manuscript highlights the chaotic behaviors of the proposed cancer model for both the commensurate and the incommensurate cases. Bifurcation diagrams, the Lyapunov exponents, and phase plots confirm the effectiveness of the conceived approach. Finally, some considerations regarding the biological meaning of the obtained results are reported through the manuscript.
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spelling pubmed-91423122022-05-28 Chaos in Cancer Tumor Growth Model with Commensurate and Incommensurate Fractional-Order Derivatives Debbouche, Nadjette Ouannas, Adel Grassi, Giuseppe Al-Hussein, Abdul-Basset A. Tahir, Fadhil Rahma Saad, Khaled M. Jahanshahi, Hadi Aly, Ayman A. Comput Math Methods Med Research Article Analyzing the dynamics of tumor-immune systems can play an important role in the fight against cancer, since it can foster the development of more effective medical treatments. This paper was aimed at making a contribution to the study of tumor-immune dynamics by presenting a new model of cancer growth based on fractional-order differential equations. By investigating the system dynamics, the manuscript highlights the chaotic behaviors of the proposed cancer model for both the commensurate and the incommensurate cases. Bifurcation diagrams, the Lyapunov exponents, and phase plots confirm the effectiveness of the conceived approach. Finally, some considerations regarding the biological meaning of the obtained results are reported through the manuscript. Hindawi 2022-05-20 /pmc/articles/PMC9142312/ /pubmed/35633919 http://dx.doi.org/10.1155/2022/5227503 Text en Copyright © 2022 Nadjette Debbouche et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Debbouche, Nadjette
Ouannas, Adel
Grassi, Giuseppe
Al-Hussein, Abdul-Basset A.
Tahir, Fadhil Rahma
Saad, Khaled M.
Jahanshahi, Hadi
Aly, Ayman A.
Chaos in Cancer Tumor Growth Model with Commensurate and Incommensurate Fractional-Order Derivatives
title Chaos in Cancer Tumor Growth Model with Commensurate and Incommensurate Fractional-Order Derivatives
title_full Chaos in Cancer Tumor Growth Model with Commensurate and Incommensurate Fractional-Order Derivatives
title_fullStr Chaos in Cancer Tumor Growth Model with Commensurate and Incommensurate Fractional-Order Derivatives
title_full_unstemmed Chaos in Cancer Tumor Growth Model with Commensurate and Incommensurate Fractional-Order Derivatives
title_short Chaos in Cancer Tumor Growth Model with Commensurate and Incommensurate Fractional-Order Derivatives
title_sort chaos in cancer tumor growth model with commensurate and incommensurate fractional-order derivatives
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142312/
https://www.ncbi.nlm.nih.gov/pubmed/35633919
http://dx.doi.org/10.1155/2022/5227503
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