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Overview of CAPICE—Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe—an EU Marie Skłodowska-Curie International Training Network
The Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER) identified child and adolescent mental illness as a priority area for research. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) is a Europ...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142454/ https://www.ncbi.nlm.nih.gov/pubmed/33474652 http://dx.doi.org/10.1007/s00787-020-01713-2 |
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author | Rajula, Hema Sekhar Reddy Manchia, Mirko Agarwal, Kratika Akingbuwa, Wonuola A. Allegrini, Andrea G. Diemer, Elizabeth Doering, Sabrina Haan, Elis Jami, Eshim S. Karhunen, Ville Leone, Marica Schellhas, Laura Thompson, Ashley van den Berg, Stéphanie M. Bergen, Sarah E. Kuja-Halkola, Ralf Hammerschlag, Anke R. Järvelin, Marjo Riitta Leval, Amy Lichtenstein, Paul Lundstrom, Sebastian Mauri, Matteo Munafò, Marcus R. Myers, David Plomin, Robert Rimfeld, Kaili Tiemeier, Henning Ystrom, Eivind Fanos, Vassilios Bartels, Meike Middeldorp, Christel M. |
author_facet | Rajula, Hema Sekhar Reddy Manchia, Mirko Agarwal, Kratika Akingbuwa, Wonuola A. Allegrini, Andrea G. Diemer, Elizabeth Doering, Sabrina Haan, Elis Jami, Eshim S. Karhunen, Ville Leone, Marica Schellhas, Laura Thompson, Ashley van den Berg, Stéphanie M. Bergen, Sarah E. Kuja-Halkola, Ralf Hammerschlag, Anke R. Järvelin, Marjo Riitta Leval, Amy Lichtenstein, Paul Lundstrom, Sebastian Mauri, Matteo Munafò, Marcus R. Myers, David Plomin, Robert Rimfeld, Kaili Tiemeier, Henning Ystrom, Eivind Fanos, Vassilios Bartels, Meike Middeldorp, Christel M. |
author_sort | Rajula, Hema Sekhar Reddy |
collection | PubMed |
description | The Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER) identified child and adolescent mental illness as a priority area for research. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) is a European Union (EU) funded training network aimed at investigating the causes of individual differences in common childhood and adolescent psychopathology, especially depression, anxiety, and attention deficit hyperactivity disorder. CAPICE brings together eight birth and childhood cohorts as well as other cohorts from the EArly Genetics and Life course Epidemiology (EAGLE) consortium, including twin cohorts, with unique longitudinal data on environmental exposures and mental health problems, and genetic data on participants. Here we describe the objectives, summarize the methodological approaches and initial results, and present the dissemination strategy of the CAPICE network. Besides identifying genetic and epigenetic variants associated with these phenotypes, analyses have been performed to shed light on the role of genetic factors and the interplay with the environment in influencing the persistence of symptoms across the lifespan. Data harmonization and building an advanced data catalogue are also part of the work plan. Findings will be disseminated to non-academic parties, in close collaboration with the Global Alliance of Mental Illness Advocacy Networks-Europe (GAMIAN-Europe). |
format | Online Article Text |
id | pubmed-9142454 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-91424542022-05-29 Overview of CAPICE—Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe—an EU Marie Skłodowska-Curie International Training Network Rajula, Hema Sekhar Reddy Manchia, Mirko Agarwal, Kratika Akingbuwa, Wonuola A. Allegrini, Andrea G. Diemer, Elizabeth Doering, Sabrina Haan, Elis Jami, Eshim S. Karhunen, Ville Leone, Marica Schellhas, Laura Thompson, Ashley van den Berg, Stéphanie M. Bergen, Sarah E. Kuja-Halkola, Ralf Hammerschlag, Anke R. Järvelin, Marjo Riitta Leval, Amy Lichtenstein, Paul Lundstrom, Sebastian Mauri, Matteo Munafò, Marcus R. Myers, David Plomin, Robert Rimfeld, Kaili Tiemeier, Henning Ystrom, Eivind Fanos, Vassilios Bartels, Meike Middeldorp, Christel M. Eur Child Adolesc Psychiatry Original Contribution The Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER) identified child and adolescent mental illness as a priority area for research. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) is a European Union (EU) funded training network aimed at investigating the causes of individual differences in common childhood and adolescent psychopathology, especially depression, anxiety, and attention deficit hyperactivity disorder. CAPICE brings together eight birth and childhood cohorts as well as other cohorts from the EArly Genetics and Life course Epidemiology (EAGLE) consortium, including twin cohorts, with unique longitudinal data on environmental exposures and mental health problems, and genetic data on participants. Here we describe the objectives, summarize the methodological approaches and initial results, and present the dissemination strategy of the CAPICE network. Besides identifying genetic and epigenetic variants associated with these phenotypes, analyses have been performed to shed light on the role of genetic factors and the interplay with the environment in influencing the persistence of symptoms across the lifespan. Data harmonization and building an advanced data catalogue are also part of the work plan. Findings will be disseminated to non-academic parties, in close collaboration with the Global Alliance of Mental Illness Advocacy Networks-Europe (GAMIAN-Europe). Springer Berlin Heidelberg 2021-01-20 2022 /pmc/articles/PMC9142454/ /pubmed/33474652 http://dx.doi.org/10.1007/s00787-020-01713-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Contribution Rajula, Hema Sekhar Reddy Manchia, Mirko Agarwal, Kratika Akingbuwa, Wonuola A. Allegrini, Andrea G. Diemer, Elizabeth Doering, Sabrina Haan, Elis Jami, Eshim S. Karhunen, Ville Leone, Marica Schellhas, Laura Thompson, Ashley van den Berg, Stéphanie M. Bergen, Sarah E. Kuja-Halkola, Ralf Hammerschlag, Anke R. Järvelin, Marjo Riitta Leval, Amy Lichtenstein, Paul Lundstrom, Sebastian Mauri, Matteo Munafò, Marcus R. Myers, David Plomin, Robert Rimfeld, Kaili Tiemeier, Henning Ystrom, Eivind Fanos, Vassilios Bartels, Meike Middeldorp, Christel M. Overview of CAPICE—Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe—an EU Marie Skłodowska-Curie International Training Network |
title | Overview of CAPICE—Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe—an EU Marie Skłodowska-Curie International Training Network |
title_full | Overview of CAPICE—Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe—an EU Marie Skłodowska-Curie International Training Network |
title_fullStr | Overview of CAPICE—Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe—an EU Marie Skłodowska-Curie International Training Network |
title_full_unstemmed | Overview of CAPICE—Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe—an EU Marie Skłodowska-Curie International Training Network |
title_short | Overview of CAPICE—Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe—an EU Marie Skłodowska-Curie International Training Network |
title_sort | overview of capice—childhood and adolescence psychopathology: unravelling the complex etiology by a large interdisciplinary collaboration in europe—an eu marie skłodowska-curie international training network |
topic | Original Contribution |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142454/ https://www.ncbi.nlm.nih.gov/pubmed/33474652 http://dx.doi.org/10.1007/s00787-020-01713-2 |
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