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Improving recombinant protein production by yeast through genome-scale modeling using proteome constraints

Eukaryotic cells are used as cell factories to produce and secrete multitudes of recombinant pharmaceutical proteins, including several of the current top-selling drugs. Due to the essential role and complexity of the secretory pathway, improvement for recombinant protein production through metaboli...

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Detalles Bibliográficos
Autores principales:	Li, Feiran, Chen, Yu, Qi, Qi, Wang, Yanyan, Yuan, Le, Huang, Mingtao, Elsemman, Ibrahim E., Feizi, Amir, Kerkhoven, Eduard J., Nielsen, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142503/ https://www.ncbi.nlm.nih.gov/pubmed/35624178 http://dx.doi.org/10.1038/s41467-022-30689-7

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