Cargando…
A free customizable tool for easy integration of microfluidics and smartphones
The integration of smartphones and microfluidics is nowadays the best possible route to achieve effective point-of-need testing (PONT), a concept increasingly demanded in the fields of human health, agriculture, food safety, and environmental monitoring. Nevertheless, efforts are still required to i...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142529/ https://www.ncbi.nlm.nih.gov/pubmed/35624294 http://dx.doi.org/10.1038/s41598-022-13099-z |
_version_ | 1784715592866988032 |
---|---|
author | Schaumburg, Federico Vidocevich, Juan P. Gerlero, Gabriel S. Pujato, Nazarena Macagno, Joana Kler, Pablo A. Berli, Claudio L. A. |
author_facet | Schaumburg, Federico Vidocevich, Juan P. Gerlero, Gabriel S. Pujato, Nazarena Macagno, Joana Kler, Pablo A. Berli, Claudio L. A. |
author_sort | Schaumburg, Federico |
collection | PubMed |
description | The integration of smartphones and microfluidics is nowadays the best possible route to achieve effective point-of-need testing (PONT), a concept increasingly demanded in the fields of human health, agriculture, food safety, and environmental monitoring. Nevertheless, efforts are still required to integrally seize all the advantages of smartphones, as well as to share the developments in easily adoptable formats. For this purpose, here we present the free platform appuente that was designed for the easy integration of microfluidic chips, smartphones, and the cloud. It includes a mobile app for end users, which provides chip identification and tracking, guidance and control, processing, smart-imaging, result reporting and cloud and Internet of Things (IoT) integration. The platform also includes a web app for PONT developers, to easily customize their mobile apps and manage the data of administered tests. Three application examples were used to validate appuente: a dummy grayscale detector that mimics quantitative colorimetric tests, a root elongation assay for pesticide toxicity assessment, and a lateral flow immunoassay for leptospirosis detection. The platform openly offers fast prototyping of smartphone apps to the wide community of lab-on-a-chip developers, and also serves as a friendly framework for new techniques, IoT integration and further capabilities. Exploiting these advantages will certainly help to enlarge the use of PONT with real-time connectivity in the near future. |
format | Online Article Text |
id | pubmed-9142529 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-91425292022-05-29 A free customizable tool for easy integration of microfluidics and smartphones Schaumburg, Federico Vidocevich, Juan P. Gerlero, Gabriel S. Pujato, Nazarena Macagno, Joana Kler, Pablo A. Berli, Claudio L. A. Sci Rep Article The integration of smartphones and microfluidics is nowadays the best possible route to achieve effective point-of-need testing (PONT), a concept increasingly demanded in the fields of human health, agriculture, food safety, and environmental monitoring. Nevertheless, efforts are still required to integrally seize all the advantages of smartphones, as well as to share the developments in easily adoptable formats. For this purpose, here we present the free platform appuente that was designed for the easy integration of microfluidic chips, smartphones, and the cloud. It includes a mobile app for end users, which provides chip identification and tracking, guidance and control, processing, smart-imaging, result reporting and cloud and Internet of Things (IoT) integration. The platform also includes a web app for PONT developers, to easily customize their mobile apps and manage the data of administered tests. Three application examples were used to validate appuente: a dummy grayscale detector that mimics quantitative colorimetric tests, a root elongation assay for pesticide toxicity assessment, and a lateral flow immunoassay for leptospirosis detection. The platform openly offers fast prototyping of smartphone apps to the wide community of lab-on-a-chip developers, and also serves as a friendly framework for new techniques, IoT integration and further capabilities. Exploiting these advantages will certainly help to enlarge the use of PONT with real-time connectivity in the near future. Nature Publishing Group UK 2022-05-27 /pmc/articles/PMC9142529/ /pubmed/35624294 http://dx.doi.org/10.1038/s41598-022-13099-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Schaumburg, Federico Vidocevich, Juan P. Gerlero, Gabriel S. Pujato, Nazarena Macagno, Joana Kler, Pablo A. Berli, Claudio L. A. A free customizable tool for easy integration of microfluidics and smartphones |
title | A free customizable tool for easy integration of microfluidics and smartphones |
title_full | A free customizable tool for easy integration of microfluidics and smartphones |
title_fullStr | A free customizable tool for easy integration of microfluidics and smartphones |
title_full_unstemmed | A free customizable tool for easy integration of microfluidics and smartphones |
title_short | A free customizable tool for easy integration of microfluidics and smartphones |
title_sort | free customizable tool for easy integration of microfluidics and smartphones |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142529/ https://www.ncbi.nlm.nih.gov/pubmed/35624294 http://dx.doi.org/10.1038/s41598-022-13099-z |
work_keys_str_mv | AT schaumburgfederico afreecustomizabletoolforeasyintegrationofmicrofluidicsandsmartphones AT vidocevichjuanp afreecustomizabletoolforeasyintegrationofmicrofluidicsandsmartphones AT gerlerogabriels afreecustomizabletoolforeasyintegrationofmicrofluidicsandsmartphones AT pujatonazarena afreecustomizabletoolforeasyintegrationofmicrofluidicsandsmartphones AT macagnojoana afreecustomizabletoolforeasyintegrationofmicrofluidicsandsmartphones AT klerpabloa afreecustomizabletoolforeasyintegrationofmicrofluidicsandsmartphones AT berliclaudiola afreecustomizabletoolforeasyintegrationofmicrofluidicsandsmartphones AT schaumburgfederico freecustomizabletoolforeasyintegrationofmicrofluidicsandsmartphones AT vidocevichjuanp freecustomizabletoolforeasyintegrationofmicrofluidicsandsmartphones AT gerlerogabriels freecustomizabletoolforeasyintegrationofmicrofluidicsandsmartphones AT pujatonazarena freecustomizabletoolforeasyintegrationofmicrofluidicsandsmartphones AT macagnojoana freecustomizabletoolforeasyintegrationofmicrofluidicsandsmartphones AT klerpabloa freecustomizabletoolforeasyintegrationofmicrofluidicsandsmartphones AT berliclaudiola freecustomizabletoolforeasyintegrationofmicrofluidicsandsmartphones |