Functional IKK/NF-κB signaling in pancreatic stellate cells is essential to prevent autoimmune pancreatitis

Pancreatic stellate cells (PSCs) are resident cells in the exocrine pancreas which contribute to pancreatic fibrogenesis and inflammation. Studies on NF-κB in pancreatitis so far focused mainly on the parenchymal and myeloid compartments. Here we show a protective immunomodulatory function of NF-κB...

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Detalles Bibliográficos
Autores principales: Chan, Lap Kwan, Tsesmelis, Miltiadis, Gerstenlauer, Melanie, Leithäuser, Frank, Kleger, Alexander, Frick, Lukas Daniel, Maier, Harald Jacob, Wirth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142538/
https://www.ncbi.nlm.nih.gov/pubmed/35624133
http://dx.doi.org/10.1038/s42003-022-03371-3

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