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The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for Plasmodium falciparum invasion

Malaria parasites such as Plasmodium falciparum have exerted formidable selective pressures on the human genome. Of the human genetic variants associated with malaria protection, beta thalassaemia (a haemoglobinopathy) was the earliest to be associated with malaria prevalence. However, the malaria p...

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Detalles Bibliográficos
Autores principales: Introini, Viola, Marin-Menendez, Alejandro, Nettesheim, Guilherme, Lin, Yen-Chun, Kariuki, Silvia N., Smith, Adrian L., Jean, Letitia, Brewin, John N., Rees, David C., Cicuta, Pietro, Rayner, Julian C., Penman, Bridget S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142571/
https://www.ncbi.nlm.nih.gov/pubmed/35624125
http://dx.doi.org/10.1038/s41598-022-12060-4