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Histone functions as a cell-surface receptor for AGEs
Reducing sugars can covalently react with proteins to generate a heterogeneous and complex group of compounds called advanced glycation end products (AGEs). AGEs are generally considered as pathogenic molecules, mediating a pro-inflammatory response and contributing to the development of a number of...
Autores principales: | Itakura, Masanori, Yamaguchi, Kosuke, Kitazawa, Roma, Lim, Sei-Young, Anan, Yusuke, Yoshitake, Jun, Shibata, Takahiro, Negishi, Lumi, Sugawa, Hikari, Nagai, Ryoji, Uchida, Koji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142594/ https://www.ncbi.nlm.nih.gov/pubmed/35624109 http://dx.doi.org/10.1038/s41467-022-30626-8 |
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