PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling

Cytotoxic stress activates stress-activated kinases, initiates adaptive mechanisms, including the unfolded protein response (UPR) and autophagy, and induces programmed cell death. Fatty acid unsaturation, controlled by stearoyl-CoA desaturase (SCD)1, prevents cytotoxic stress but the mechanisms are...

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Detalles Bibliográficos
Autores principales: Thürmer, Maria, Gollowitzer, André, Pein, Helmut, Neukirch, Konstantin, Gelmez, Elif, Waltl, Lorenz, Wielsch, Natalie, Winkler, René, Löser, Konstantin, Grander, Julia, Hotze, Madlen, Harder, Sönke, Döding, Annika, Meßner, Martina, Troisi, Fabiana, Ardelt, Maximilian, Schlüter, Hartmut, Pachmayr, Johanna, Gutiérrez-Gutiérrez, Óscar, Rudolph, Karl Lenhard, Thedieck, Kathrin, Schulze-Späte, Ulrike, González-Estévez, Cristina, Kosan, Christian, Svatoš, Aleš, Kwiatkowski, Marcel, Koeberle, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142606/
https://www.ncbi.nlm.nih.gov/pubmed/35624087
http://dx.doi.org/10.1038/s41467-022-30374-9

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