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The role of Ivor Lewis esophagectomy in the treatment of achalasia with megaesophagus: A case report

INTRODUCTION: Achalasia with megaesophagus is a pathology characterized by widespread and irregular dilation of the esophageal lumen. In most cases, this dilation is caused by contraction and subsequent failed relaxation of the lower esophageal sphincter (LES). It may be associated with a partial or...

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Autores principales: Zini Radaelli, Lorenzo Federico, Aramini, Beatrice, Ciarrocchi, Angelo Paolo, Sanna, Stefano, Argnani, Desideria, Stella, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142608/
https://www.ncbi.nlm.nih.gov/pubmed/35638078
http://dx.doi.org/10.1016/j.amsu.2022.103630
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author Zini Radaelli, Lorenzo Federico
Aramini, Beatrice
Ciarrocchi, Angelo Paolo
Sanna, Stefano
Argnani, Desideria
Stella, Franco
author_facet Zini Radaelli, Lorenzo Federico
Aramini, Beatrice
Ciarrocchi, Angelo Paolo
Sanna, Stefano
Argnani, Desideria
Stella, Franco
author_sort Zini Radaelli, Lorenzo Federico
collection PubMed
description INTRODUCTION: Achalasia with megaesophagus is a pathology characterized by widespread and irregular dilation of the esophageal lumen. In most cases, this dilation is caused by contraction and subsequent failed relaxation of the lower esophageal sphincter (LES). It may be associated with a partial or complete slowing of the esophageal peristalsis. CASE OVERVIEW: We present the case of a 58-year-old woman who developed dysphagia, regurgitation, and substantial weight loss (11 kg) over a span of 1 year. Symptomatic achalasia with megaesophagus was diagnosed following chest and abdominal computed tomography (CT) with contrast and transit RX with gastrografin and esophageal manometry. The patient refuse all minimally endoscopic treatments and opted straightly for the treatment with esophagectomy sec. Ivor–Lewis. At the 6-month follow-up, the patient appeared in excellent general clinical condition and oral gastrografin radiography (OGR) showed good channeling. DISCUSSION: Patients require medical attention when presenting with achalasia that has eroded the esophageal wall enough to form a megaesophagus. Early and minimally invasive treatments (i.e., medical therapy, endoscopic dilation, and myotomy) are insufficient at this stage, and thus esophageal surgery is required. Among the most common surgical approaches, we must mention esophagectomy sec. McKeown and esophagectomy with interposition of a colic loop sec. Wilkins; however, based on our experience, esophagectomy sec. Ivor–Lewis with intrathoracic anastomosis leads to excellent results and can therefore be considered a valid alternative for treating complex cases. CONCLUSIONS: Subtotal esophagectomy sec. Ivor–Lewis with intrathoracic anastomosis is effective in treating achalasia with megaesophagus.
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spelling pubmed-91426082022-05-29 The role of Ivor Lewis esophagectomy in the treatment of achalasia with megaesophagus: A case report Zini Radaelli, Lorenzo Federico Aramini, Beatrice Ciarrocchi, Angelo Paolo Sanna, Stefano Argnani, Desideria Stella, Franco Ann Med Surg (Lond) Case Report INTRODUCTION: Achalasia with megaesophagus is a pathology characterized by widespread and irregular dilation of the esophageal lumen. In most cases, this dilation is caused by contraction and subsequent failed relaxation of the lower esophageal sphincter (LES). It may be associated with a partial or complete slowing of the esophageal peristalsis. CASE OVERVIEW: We present the case of a 58-year-old woman who developed dysphagia, regurgitation, and substantial weight loss (11 kg) over a span of 1 year. Symptomatic achalasia with megaesophagus was diagnosed following chest and abdominal computed tomography (CT) with contrast and transit RX with gastrografin and esophageal manometry. The patient refuse all minimally endoscopic treatments and opted straightly for the treatment with esophagectomy sec. Ivor–Lewis. At the 6-month follow-up, the patient appeared in excellent general clinical condition and oral gastrografin radiography (OGR) showed good channeling. DISCUSSION: Patients require medical attention when presenting with achalasia that has eroded the esophageal wall enough to form a megaesophagus. Early and minimally invasive treatments (i.e., medical therapy, endoscopic dilation, and myotomy) are insufficient at this stage, and thus esophageal surgery is required. Among the most common surgical approaches, we must mention esophagectomy sec. McKeown and esophagectomy with interposition of a colic loop sec. Wilkins; however, based on our experience, esophagectomy sec. Ivor–Lewis with intrathoracic anastomosis leads to excellent results and can therefore be considered a valid alternative for treating complex cases. CONCLUSIONS: Subtotal esophagectomy sec. Ivor–Lewis with intrathoracic anastomosis is effective in treating achalasia with megaesophagus. Elsevier 2022-04-14 /pmc/articles/PMC9142608/ /pubmed/35638078 http://dx.doi.org/10.1016/j.amsu.2022.103630 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Zini Radaelli, Lorenzo Federico
Aramini, Beatrice
Ciarrocchi, Angelo Paolo
Sanna, Stefano
Argnani, Desideria
Stella, Franco
The role of Ivor Lewis esophagectomy in the treatment of achalasia with megaesophagus: A case report
title The role of Ivor Lewis esophagectomy in the treatment of achalasia with megaesophagus: A case report
title_full The role of Ivor Lewis esophagectomy in the treatment of achalasia with megaesophagus: A case report
title_fullStr The role of Ivor Lewis esophagectomy in the treatment of achalasia with megaesophagus: A case report
title_full_unstemmed The role of Ivor Lewis esophagectomy in the treatment of achalasia with megaesophagus: A case report
title_short The role of Ivor Lewis esophagectomy in the treatment of achalasia with megaesophagus: A case report
title_sort role of ivor lewis esophagectomy in the treatment of achalasia with megaesophagus: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142608/
https://www.ncbi.nlm.nih.gov/pubmed/35638078
http://dx.doi.org/10.1016/j.amsu.2022.103630
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