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Diagnosis and management of Henoch-Schonlein purpura in Indonesian elderly with severe complication: A rare case

BACKGROUND: Henoch-Schonlein purpura (HSP) in the elderly is very rare, so this case report was conducted to improve the diagnosis and management of HSP. CASE PRESENTATION: A 65-year-old Indonesian male with severe complications of HSP had been reported. In addition to the patient's history, ph...

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Autores principales: Putri, Arinditia Triasti, Awalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142633/
https://www.ncbi.nlm.nih.gov/pubmed/35637989
http://dx.doi.org/10.1016/j.amsu.2022.103650
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author Putri, Arinditia Triasti
Awalia
author_facet Putri, Arinditia Triasti
Awalia
author_sort Putri, Arinditia Triasti
collection PubMed
description BACKGROUND: Henoch-Schonlein purpura (HSP) in the elderly is very rare, so this case report was conducted to improve the diagnosis and management of HSP. CASE PRESENTATION: A 65-year-old Indonesian male with severe complications of HSP had been reported. In addition to the patient's history, physical examination, laboratory and radiological findings, he performed a left sole anterior biopsy that showed interstitial infiltrate of main neutrophils, and faint granular deposits of IgA and C3 seen within the superficial vessels. He also had severe complications of gastrointestinal bleeding, extensive leukocytoclastic skin vasculitis, renal, and neurological manifestations. He had been given a pulse steroid, cyclophosphamide. He also planned to receive rituximab but canceled due to his worsening condition. DISCUSSION: Poor prognosis in the management of HSP in the elderly needs more attention to minimize mortality. CONCLUSION: Management of HSP in the elderly patient is challenging as it is a rare case, with a tendency for severe manifestations and rapid progression.
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spelling pubmed-91426332022-05-29 Diagnosis and management of Henoch-Schonlein purpura in Indonesian elderly with severe complication: A rare case Putri, Arinditia Triasti Awalia Ann Med Surg (Lond) Case Report BACKGROUND: Henoch-Schonlein purpura (HSP) in the elderly is very rare, so this case report was conducted to improve the diagnosis and management of HSP. CASE PRESENTATION: A 65-year-old Indonesian male with severe complications of HSP had been reported. In addition to the patient's history, physical examination, laboratory and radiological findings, he performed a left sole anterior biopsy that showed interstitial infiltrate of main neutrophils, and faint granular deposits of IgA and C3 seen within the superficial vessels. He also had severe complications of gastrointestinal bleeding, extensive leukocytoclastic skin vasculitis, renal, and neurological manifestations. He had been given a pulse steroid, cyclophosphamide. He also planned to receive rituximab but canceled due to his worsening condition. DISCUSSION: Poor prognosis in the management of HSP in the elderly needs more attention to minimize mortality. CONCLUSION: Management of HSP in the elderly patient is challenging as it is a rare case, with a tendency for severe manifestations and rapid progression. Elsevier 2022-04-20 /pmc/articles/PMC9142633/ /pubmed/35637989 http://dx.doi.org/10.1016/j.amsu.2022.103650 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Putri, Arinditia Triasti
Awalia
Diagnosis and management of Henoch-Schonlein purpura in Indonesian elderly with severe complication: A rare case
title Diagnosis and management of Henoch-Schonlein purpura in Indonesian elderly with severe complication: A rare case
title_full Diagnosis and management of Henoch-Schonlein purpura in Indonesian elderly with severe complication: A rare case
title_fullStr Diagnosis and management of Henoch-Schonlein purpura in Indonesian elderly with severe complication: A rare case
title_full_unstemmed Diagnosis and management of Henoch-Schonlein purpura in Indonesian elderly with severe complication: A rare case
title_short Diagnosis and management of Henoch-Schonlein purpura in Indonesian elderly with severe complication: A rare case
title_sort diagnosis and management of henoch-schonlein purpura in indonesian elderly with severe complication: a rare case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142633/
https://www.ncbi.nlm.nih.gov/pubmed/35637989
http://dx.doi.org/10.1016/j.amsu.2022.103650
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