Cargando…

Connectivity in eQTL networks dictates reproducibility and genomic properties

Expression quantitative trait locus (eQTL) analysis associates SNPs with gene expression; these relationships can be represented as a bipartite network with association strength as “edge weights” between SNPs and genes. However, most eQTL networks use binary edge weights based on thresholded FDR est...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaynor, Sheila M., Fagny, Maud, Lin, Xihong, Platig, John, Quackenbush, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142682/
https://www.ncbi.nlm.nih.gov/pubmed/35637906
http://dx.doi.org/10.1016/j.crmeth.2022.100218