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Gut microbiota-derived ursodeoxycholic acid from neonatal dairy calves improves intestinal homeostasis and colitis to attenuate extended-spectrum β-lactamase-producing enteroaggregative Escherichia coli infection

BACKGROUND: Antimicrobials are often used to prevent and treat diarrhea induced by enteroaggregative Escherichia coli (EAEC) in young ruminants. However, drug overuse or misuse accelerates the spread of multidrug-resistant extended-spectrum β-lactamase (ESBL)-producing E. coli. Thus, supplementary f...

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Detalles Bibliográficos
Autores principales: He, Zhiyuan, Ma, Yulin, Yang, Sirui, Zhang, Shuyuan, Liu, Shuai, Xiao, Jianxin, Wang, Yajing, Wang, Wei, Yang, Hongjian, Li, Shengli, Cao, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142728/
https://www.ncbi.nlm.nih.gov/pubmed/35643532
http://dx.doi.org/10.1186/s40168-022-01269-0