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Preparation, Characterization, and Evaluation of Breviscapine Nanosuspension and Its Freeze-Dried Powder

As a biopharmaceutics classification system (BCS) class IV drug, breviscapine (Bre) has low solubility in water, poor chemical stability, a short biological half-life and rapid removal from plasma. This paper prepared a Bre nanosuspension (Bre-NS) by an ultrasound-assisted anti-solvent precipitation...

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Detalles Bibliográficos
Autores principales:	Zhang, Ting, Li, Xixi, Xu, Juewen, Shao, Jingbao, Ding, Meihong, Shi, Senlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143020/ https://www.ncbi.nlm.nih.gov/pubmed/35631508 http://dx.doi.org/10.3390/pharmaceutics14050923

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