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A Bivalent COVID-19 Vaccine Based on Alpha and Beta Variants Elicits Potent and Broad Immune Responses in Mice against SARS-CoV-2 Variants

With the emergence and rapid spread of new pandemic variants, especially variants of concern (VOCs), the development of next-generation vaccines with broad-spectrum neutralizing activities is of great importance. In this study, SCTV01C, a clinical stage bivalent vaccine based on trimeric spike extra...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Sun, Chunyun, Ma, Juan, Yu, Chulin, Kong, Desheng, Chen, Meng, Liu, Xuejie, Zhao, Dandan, Gao, Shuman, Kou, Shuyuan, Sun, Lili, Ge, Zeyong, Zhao, Jun, Li, Kuokuo, Zhang, Tao, Zhang, Yanjing, Luo, Chunxia, Li, Xuefeng, Wang, Yang, Xie, Liangzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143086/
https://www.ncbi.nlm.nih.gov/pubmed/35632456
http://dx.doi.org/10.3390/vaccines10050702