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Sex Differences in Intestinal P-Glycoprotein Expression in Wistar versus Sprague Dawley Rats
Wistar and Sprague Dawley are the most common strains of rat used in pharmaceutical research and are used interchangeably in pre-clinical drug development. No studies have assessed whether Wistar and Sprague Dawley rats are equivalent in the gastrointestinal factors that influence oral drug absorpti...
Autores principales: | Madla, Christine M., Qin, Yujia, Gavins, Francesca K. H., Liu, Jing, Dou, Liu, Orlu, Mine, Murdan, Sudaxshina, Mai, Yang, Basit, Abdul W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143158/ https://www.ncbi.nlm.nih.gov/pubmed/35631615 http://dx.doi.org/10.3390/pharmaceutics14051030 |
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