Cargando…

Evaluation of 3-Borono-l-Phenylalanine as a Water-Soluble Boron Neutron Capture Therapy Agent

Although 4-borono-l-phenylalanine (4-BPA) is currently the only marketed agent available for boron neutron capture therapy (BNCT), its low water solubility raises concerns. In this study, we synthesized 3-borono-l-phenylalanine (3-BPA), a positional isomer of 4-BPA, with improved water solubility. W...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kondo, Naoya, Hirano, Fuko, Temma, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143228/ https://www.ncbi.nlm.nih.gov/pubmed/35631692 http://dx.doi.org/10.3390/pharmaceutics14051106

Ejemplares similares

Reliable radiosynthesis of 4-[(10)B]borono-2-[(18)F]fluoro-l-phenylalanine with quality assurance for boron neutron capture therapy-oriented diagnosis
por: Ishiwata, Kiichi, et al.
Publicado: (2018)

4-Borono-2-(18)F-fluoro-l-phenylalanine PET for boron neutron capture therapy-oriented diagnosis: overview of a quarter century of research
por: Ishiwata, Kiichi
Publicado: (2019)

Non‐invasive estimation of (10)B‐4‐borono‐L‐phenylalanine‐derived boron concentration in tumors by PET using 4‐borono‐2‐(18)F‐fluoro‐phenylalanine
por: Yoshimoto, Mitsuyoshi, et al.
Publicado: (2018)

Development of a 2-(2-Hydroxyphenyl)-1H-benzimidazole-Based Fluorescence Sensor Targeting Boronic Acids for Versatile Application in Boron Neutron Capture Therapy
por: Kondo, Naoya, et al.
Publicado: (2023)

Dynamic changes in (18)F-borono-L-phenylalanine uptake in unresectable, advanced, or recurrent squamous cell carcinoma of the head and neck and malignant melanoma during boron neutron capture therapy patient selection
por: Morita, Takahiro, et al.
Publicado: (2018)

Comparison of the image-derived radioactivity and blood-sample radioactivity for estimating the clinical indicators of the efficacy of boron neutron capture therapy (BNCT): 4-borono-2-(18)F-fluoro-phenylalanine (FBPA) PET study
por: Isohashi, Kayako, et al.
Publicado: (2016)

A Red-Emitting Fluorescence Sensor for Detecting Boronic Acid-Containing Agents in Cells
por: Kondo, Naoya, et al.
Publicado: (2022)

Boron delivery agents for neutron capture therapy of cancer
por: Barth, Rolf F., et al.
Publicado: (2018)

Multi-Functional Boron-Delivery Agents for Boron Neutron Capture Therapy of Cancers
por: Oloo, Sebastian O., et al.
Publicado: (2023)

The dependency of compound biological effectiveness factors on the type and the concentration of administered neutron capture agents in boron neutron capture therapy
por: Masunaga, Shin-ichiro, et al.
Publicado: (2014)

Nanostructured Boron Nitride With High Water Dispersibility For Boron Neutron Capture Therapy
por: Singh, Bikramjeet, et al.
Publicado: (2016)

Anomeric sugar boronic acid analogues as potential agents for boron neutron capture therapy
por: Imperio, Daniela, et al.
Publicado: (2019)

Investigation of the Impact of L-Phenylalanine and L-Tyrosine Pre-Treatment on the Uptake of 4-Borono-L-Phenylalanine in Cancerous and Normal Cells Using an Analytical Approach Based on SC-ICP-MS
por: Balcer, Emilia, et al.
Publicado: (2023)

Boron Neutron Capture Therapy for Malignant Brain Tumors
por: MIYATAKE, Shin-Ichi, et al.
Publicado: (2016)

Theranostics in Boron Neutron Capture Therapy
por: Sauerwein, Wolfgang A. G., et al.
Publicado: (2021)

Relationship between the uptake of (18)F-borono-L-phenylalanine and L-[methyl-(11)C] methionine in head and neck tumors and normal organs
por: Watanabe, Yoshiaki, et al.
Publicado: (2017)

Correlation between L‐amino acid transporter 1 expression and 4‐borono‐2‐(18)F‐fluoro‐phenylalanine accumulation in humans
por: Kashihara, Tairo, et al.
Publicado: (2023)

Analysis of boron neutron capture reaction sensitivity using Monte Carlo simulation and proposal of a new dosimetry index in boron neutron capture therapy
por: Takeno, Satoshi, et al.
Publicado: (2022)

Boron-peptide conjugates with angiopep-2 for boron neutron capture therapy
por: Xiang, Jing, et al.
Publicado: (2023)

Water-Soluble closo-Docecaborate-Containing Pteroyl Derivatives Targeting Folate Receptor-Positive Tumors for Boron Neutron Capture Therapy
por: Nakagawa, Fumiko, et al.
Publicado: (2020)

A Novel Boron Lipid to Modify Liposomal Surfaces for Boron Neutron Capture Therapy
por: Shirakawa, Makoto, et al.
Publicado: (2021)

Molecularly Imprinted Polymers Specific towards 4-Borono-L-phenylalanine—Synthesis Optimization, Theoretical Analysis, Morphology Investigation, Cytotoxicity, and Release Studies
por: Balcer, Emilia, et al.
Publicado: (2023)

Conference on Accelerator-based Neutron Sources for Boron Neutron Capture Therapy
Publicado: (1994)

Neutron Tube Design Study for Boron Neutron Capture Therapy Application
por: Verbeke, J M, et al.
Publicado: (1999)

Applicability of Combination with Tirapazamine in Boron Neutron Capture Therapy
por: Masunaga, Shin‐ichiro, et al.
Publicado: (1998)

Development of an Imaging Technique for Boron Neutron Capture Therapy
por: Fukumitsu, Nobuyoshi, et al.
Publicado: (2021)

Boron Neutron Capture Therapy: Current Status and Challenges
por: Wang, Song, et al.
Publicado: (2022)

Boron microlocalization in oral mucosal tissue: implications for boron neutron capture therapy
por: Morris, G M, et al.
Publicado: (2000)

Optimal Neutron Source and Beam Shaping Assembly for Boron Neutron Capture Therapy
por: Vujic, J L, et al.
Publicado: (2003)

Diffuse bone marrow uptake related to granulocyte colony-stimulating factor-producing maxillary sinus carcinoma on 4-borono-2-(18)F-fluoro-L-phenylalanine positron emission tomography/computed tomography
por: Kusumahstuti, Kharisma Perdani, et al.
Publicado: (2020)

Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB(0,+), LAT1 and LAT2
por: Wongthai, Printip, et al.
Publicado: (2015)

High Boron-loaded DNA-Oligomers as Potential Boron Neutron Capture Therapy and Antisense Oligonucleotide Dual-Action Anticancer Agents (‡)
por: Kaniowski, Damian, et al.
Publicado: (2017)

Boron rich nanotube drug carrier system is suited for boron neutron capture therapy
por: Heide, Fabian, et al.
Publicado: (2021)

Glioma Stem-Like Cells Can Be Targeted in Boron Neutron Capture Therapy with Boronophenylalanine
por: Kondo, Natsuko, et al.
Publicado: (2020)

An Assessment of the Potential Use of BNNTs for Boron Neutron Capture Therapy
por: Ferreira, Tiago H., et al.
Publicado: (2017)

Boron neutron capture therapy: Current status and future perspectives
por: Dymova, Mayya Alexandrovna, et al.
Publicado: (2020)

Boron Neutron Capture Therapy: A Review of Clinical Applications
por: Malouff, Timothy D., et al.
Publicado: (2021)

The basis and advances in clinical application of boron neutron capture therapy
por: He, Huifang, et al.
Publicado: (2021)

Boron Neutron Capture Therapy: From Nuclear Physics to Biomedicine
por: Bortolussi, Silva, et al.
Publicado: (2021)

Boron Neutron Capture Therapy: Clinical Application and Research Progress
por: Cheng, Xiang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_cen2e5np3sq8tpcubifl377n94