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Parapoxvirus Interleukin-10 Homologues Vary in Their Receptor Binding, Anti-Inflammatory, and Stimulatory Activities

Homologues of interleukin (IL)-10, a pleiotropic immunomodulatory cytokine, have been identified in the Parapoxvirus genus. The first identified, Orf virus (ORFV) IL-10, greatly enhanced infection of its host, exhibiting immune modulatory effects equivalent to human IL-10. IL-10-like genes were then...

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Detalles Bibliográficos
Autores principales: Naqash, Amreen, Stuart, Gabriella, Kemp, Roslyn, Wise, Lyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143231/
https://www.ncbi.nlm.nih.gov/pubmed/35631028
http://dx.doi.org/10.3390/pathogens11050507

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