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Emerging Trends in Genetic Engineering of Microalgae for Commercial Applications
Recently, microalgal biotechnology has received increasing interests in producing valuable, sustainable and environmentally friendly bioproducts. The development of economically viable production processes entails resolving certain limitations of microalgal biotechnology, and fast evolving genetic e...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143385/ https://www.ncbi.nlm.nih.gov/pubmed/35621936 http://dx.doi.org/10.3390/md20050285 |
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author | Grama, Samir B. Liu, Zhiyuan Li, Jian |
author_facet | Grama, Samir B. Liu, Zhiyuan Li, Jian |
author_sort | Grama, Samir B. |
collection | PubMed |
description | Recently, microalgal biotechnology has received increasing interests in producing valuable, sustainable and environmentally friendly bioproducts. The development of economically viable production processes entails resolving certain limitations of microalgal biotechnology, and fast evolving genetic engineering technologies have emerged as new tools to overcome these limitations. This review provides a synopsis of recent progress, current trends and emerging approaches of genetic engineering of microalgae for commercial applications, including production of pharmaceutical protein, lipid, carotenoids and biohydrogen, etc. Photochemistry improvement in microalgae and CO(2) sequestration by microalgae via genetic engineering were also discussed since these subjects are closely entangled with commercial production of the above mentioned products. Although genetic engineering of microalgae is proved to be very effective in boosting performance of production in laboratory conditions, only limited success was achieved to be applicable to industry so far. With genetic engineering technologies advancing rapidly and intensive investigations going on, more bioproducts are expected to be produced by genetically modified microalgae and even much more to be prospected. |
format | Online Article Text |
id | pubmed-9143385 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91433852022-05-29 Emerging Trends in Genetic Engineering of Microalgae for Commercial Applications Grama, Samir B. Liu, Zhiyuan Li, Jian Mar Drugs Review Recently, microalgal biotechnology has received increasing interests in producing valuable, sustainable and environmentally friendly bioproducts. The development of economically viable production processes entails resolving certain limitations of microalgal biotechnology, and fast evolving genetic engineering technologies have emerged as new tools to overcome these limitations. This review provides a synopsis of recent progress, current trends and emerging approaches of genetic engineering of microalgae for commercial applications, including production of pharmaceutical protein, lipid, carotenoids and biohydrogen, etc. Photochemistry improvement in microalgae and CO(2) sequestration by microalgae via genetic engineering were also discussed since these subjects are closely entangled with commercial production of the above mentioned products. Although genetic engineering of microalgae is proved to be very effective in boosting performance of production in laboratory conditions, only limited success was achieved to be applicable to industry so far. With genetic engineering technologies advancing rapidly and intensive investigations going on, more bioproducts are expected to be produced by genetically modified microalgae and even much more to be prospected. MDPI 2022-04-24 /pmc/articles/PMC9143385/ /pubmed/35621936 http://dx.doi.org/10.3390/md20050285 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Grama, Samir B. Liu, Zhiyuan Li, Jian Emerging Trends in Genetic Engineering of Microalgae for Commercial Applications |
title | Emerging Trends in Genetic Engineering of Microalgae for Commercial Applications |
title_full | Emerging Trends in Genetic Engineering of Microalgae for Commercial Applications |
title_fullStr | Emerging Trends in Genetic Engineering of Microalgae for Commercial Applications |
title_full_unstemmed | Emerging Trends in Genetic Engineering of Microalgae for Commercial Applications |
title_short | Emerging Trends in Genetic Engineering of Microalgae for Commercial Applications |
title_sort | emerging trends in genetic engineering of microalgae for commercial applications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143385/ https://www.ncbi.nlm.nih.gov/pubmed/35621936 http://dx.doi.org/10.3390/md20050285 |
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