Cargando…

Pathogen- and Type-Specific Changes in Invasive Bacterial Disease Epidemiology during the First Year of the COVID-19 Pandemic in The Netherlands

COVID-19 control measures have resulted in a decline in invasive bacterial disease caused by Neisseria meningitidis (IMD), Streptococcus pneumoniae (IPD), and Haemophilus influenzae (Hi-D). These species comprise different serogroups and serotypes that impact transmissibility and virulence. We evalu...

Descripción completa

Detalles Bibliográficos
Autores principales: Steens, Anneke, Knol, Mirjam J., Freudenburg-de Graaf, Wieke, de Melker, Hester E., van der Ende, Arie, van Sorge, Nina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143569/
https://www.ncbi.nlm.nih.gov/pubmed/35630415
http://dx.doi.org/10.3390/microorganisms10050972
_version_ 1784715838329192448
author Steens, Anneke
Knol, Mirjam J.
Freudenburg-de Graaf, Wieke
de Melker, Hester E.
van der Ende, Arie
van Sorge, Nina M.
author_facet Steens, Anneke
Knol, Mirjam J.
Freudenburg-de Graaf, Wieke
de Melker, Hester E.
van der Ende, Arie
van Sorge, Nina M.
author_sort Steens, Anneke
collection PubMed
description COVID-19 control measures have resulted in a decline in invasive bacterial disease caused by Neisseria meningitidis (IMD), Streptococcus pneumoniae (IPD), and Haemophilus influenzae (Hi-D). These species comprise different serogroups and serotypes that impact transmissibility and virulence. We evaluated type- and pathogen-specific changes in invasive bacterial disease epidemiology in the Netherlands during the first year of the SARS-CoV-2 pandemic. Cases were based on nationwide surveillance for five bacterial species with either respiratory (IMD, IPD, Hi-D) or non-respiratory (controls) transmission routes and were compared from the pre-COVID period (April 2015–March 2020) to the first COVID-19 year (April 2020–March 2021). IMD, IPD, and Hi-D cases decreased by 78%, 67%, and 35%, respectively, in the first COVID-19 year compared to the pre-COVID period, although effects differed per age group. Serogroup B-IMD declined by 61%, while serogroup W and Y-IMD decreased >90%. IPD caused by serotypes 7F, 15A, 12F, 33F, and 8 showed the most pronounced decline (≥76%). In contrast to an overall decrease in Hi-D cases, vaccine-preventable serotype b (Hib) increased by 51%. COVID-19 control measures had pathogen- and type-specific effects related to invasive infections. Continued surveillance is critical to monitor potential rebound effects once restriction measures are lifted and transmission is resumed.
format Online
Article
Text
id pubmed-9143569
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-91435692022-05-29 Pathogen- and Type-Specific Changes in Invasive Bacterial Disease Epidemiology during the First Year of the COVID-19 Pandemic in The Netherlands Steens, Anneke Knol, Mirjam J. Freudenburg-de Graaf, Wieke de Melker, Hester E. van der Ende, Arie van Sorge, Nina M. Microorganisms Article COVID-19 control measures have resulted in a decline in invasive bacterial disease caused by Neisseria meningitidis (IMD), Streptococcus pneumoniae (IPD), and Haemophilus influenzae (Hi-D). These species comprise different serogroups and serotypes that impact transmissibility and virulence. We evaluated type- and pathogen-specific changes in invasive bacterial disease epidemiology in the Netherlands during the first year of the SARS-CoV-2 pandemic. Cases were based on nationwide surveillance for five bacterial species with either respiratory (IMD, IPD, Hi-D) or non-respiratory (controls) transmission routes and were compared from the pre-COVID period (April 2015–March 2020) to the first COVID-19 year (April 2020–March 2021). IMD, IPD, and Hi-D cases decreased by 78%, 67%, and 35%, respectively, in the first COVID-19 year compared to the pre-COVID period, although effects differed per age group. Serogroup B-IMD declined by 61%, while serogroup W and Y-IMD decreased >90%. IPD caused by serotypes 7F, 15A, 12F, 33F, and 8 showed the most pronounced decline (≥76%). In contrast to an overall decrease in Hi-D cases, vaccine-preventable serotype b (Hib) increased by 51%. COVID-19 control measures had pathogen- and type-specific effects related to invasive infections. Continued surveillance is critical to monitor potential rebound effects once restriction measures are lifted and transmission is resumed. MDPI 2022-05-05 /pmc/articles/PMC9143569/ /pubmed/35630415 http://dx.doi.org/10.3390/microorganisms10050972 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Steens, Anneke
Knol, Mirjam J.
Freudenburg-de Graaf, Wieke
de Melker, Hester E.
van der Ende, Arie
van Sorge, Nina M.
Pathogen- and Type-Specific Changes in Invasive Bacterial Disease Epidemiology during the First Year of the COVID-19 Pandemic in The Netherlands
title Pathogen- and Type-Specific Changes in Invasive Bacterial Disease Epidemiology during the First Year of the COVID-19 Pandemic in The Netherlands
title_full Pathogen- and Type-Specific Changes in Invasive Bacterial Disease Epidemiology during the First Year of the COVID-19 Pandemic in The Netherlands
title_fullStr Pathogen- and Type-Specific Changes in Invasive Bacterial Disease Epidemiology during the First Year of the COVID-19 Pandemic in The Netherlands
title_full_unstemmed Pathogen- and Type-Specific Changes in Invasive Bacterial Disease Epidemiology during the First Year of the COVID-19 Pandemic in The Netherlands
title_short Pathogen- and Type-Specific Changes in Invasive Bacterial Disease Epidemiology during the First Year of the COVID-19 Pandemic in The Netherlands
title_sort pathogen- and type-specific changes in invasive bacterial disease epidemiology during the first year of the covid-19 pandemic in the netherlands
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143569/
https://www.ncbi.nlm.nih.gov/pubmed/35630415
http://dx.doi.org/10.3390/microorganisms10050972
work_keys_str_mv AT steensanneke pathogenandtypespecificchangesininvasivebacterialdiseaseepidemiologyduringthefirstyearofthecovid19pandemicinthenetherlands
AT knolmirjamj pathogenandtypespecificchangesininvasivebacterialdiseaseepidemiologyduringthefirstyearofthecovid19pandemicinthenetherlands
AT freudenburgdegraafwieke pathogenandtypespecificchangesininvasivebacterialdiseaseepidemiologyduringthefirstyearofthecovid19pandemicinthenetherlands
AT demelkerhestere pathogenandtypespecificchangesininvasivebacterialdiseaseepidemiologyduringthefirstyearofthecovid19pandemicinthenetherlands
AT vanderendearie pathogenandtypespecificchangesininvasivebacterialdiseaseepidemiologyduringthefirstyearofthecovid19pandemicinthenetherlands
AT vansorgeninam pathogenandtypespecificchangesininvasivebacterialdiseaseepidemiologyduringthefirstyearofthecovid19pandemicinthenetherlands