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Use of Image-Guided Surgical Navigation during Resection of Locally Recurrent Rectal Cancer

Surgery for locally recurrent rectal cancer (LRRC) presents several challenges, which is why the percentage of inadequate resections of these tumors is high. In this exploratory study, we evaluate the use of image-guided surgical navigation during resection of LRRC. Patients who were scheduled to un...

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Autores principales: Groen, Harald C., den Hartog, Anne G., Heerink, Wouter J., Kuhlmann, Koert F. D., Kok, Niels F. M., van Veen, Ruben, Hiep, Marijn A. J., Snaebjornsson, Petur, Grotenhuis, Brechtje A., Beets, Geerard L., Aalbers, Arend G. J., Ruers, Theo J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143650/
https://www.ncbi.nlm.nih.gov/pubmed/35629313
http://dx.doi.org/10.3390/life12050645
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author Groen, Harald C.
den Hartog, Anne G.
Heerink, Wouter J.
Kuhlmann, Koert F. D.
Kok, Niels F. M.
van Veen, Ruben
Hiep, Marijn A. J.
Snaebjornsson, Petur
Grotenhuis, Brechtje A.
Beets, Geerard L.
Aalbers, Arend G. J.
Ruers, Theo J. M.
author_facet Groen, Harald C.
den Hartog, Anne G.
Heerink, Wouter J.
Kuhlmann, Koert F. D.
Kok, Niels F. M.
van Veen, Ruben
Hiep, Marijn A. J.
Snaebjornsson, Petur
Grotenhuis, Brechtje A.
Beets, Geerard L.
Aalbers, Arend G. J.
Ruers, Theo J. M.
author_sort Groen, Harald C.
collection PubMed
description Surgery for locally recurrent rectal cancer (LRRC) presents several challenges, which is why the percentage of inadequate resections of these tumors is high. In this exploratory study, we evaluate the use of image-guided surgical navigation during resection of LRRC. Patients who were scheduled to undergo surgical resection of LRRC who were deemed by the multidisciplinary team to be at a high risk of inadequate tumor resection were selected to undergo surgical navigation. The risk of inadequate surgery was further determined by the proximity of the tumor to critical anatomical structures. Workflow characteristics of the surgical navigation procedure were evaluated, while the surgical outcome was determined by the status of the resection margin. In total, 20 patients were analyzed. For all procedures, surgical navigation was completed successfully and demonstrated to be accurate, while no complications related to the surgical navigation were discerned. Radical resection was achieved in 14 cases (70%). In five cases (25%), a tumor-positive resection margin (R1) was anticipated during surgery, as extensive radical resection was determined to be compromised. These patients all received intraoperative brachytherapy. In one case (5%), an unexpected R1 resection was performed. Surgical navigation during resection of LRRC is thus safe and feasible and enables accurate surgical guidance.
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spelling pubmed-91436502022-05-29 Use of Image-Guided Surgical Navigation during Resection of Locally Recurrent Rectal Cancer Groen, Harald C. den Hartog, Anne G. Heerink, Wouter J. Kuhlmann, Koert F. D. Kok, Niels F. M. van Veen, Ruben Hiep, Marijn A. J. Snaebjornsson, Petur Grotenhuis, Brechtje A. Beets, Geerard L. Aalbers, Arend G. J. Ruers, Theo J. M. Life (Basel) Article Surgery for locally recurrent rectal cancer (LRRC) presents several challenges, which is why the percentage of inadequate resections of these tumors is high. In this exploratory study, we evaluate the use of image-guided surgical navigation during resection of LRRC. Patients who were scheduled to undergo surgical resection of LRRC who were deemed by the multidisciplinary team to be at a high risk of inadequate tumor resection were selected to undergo surgical navigation. The risk of inadequate surgery was further determined by the proximity of the tumor to critical anatomical structures. Workflow characteristics of the surgical navigation procedure were evaluated, while the surgical outcome was determined by the status of the resection margin. In total, 20 patients were analyzed. For all procedures, surgical navigation was completed successfully and demonstrated to be accurate, while no complications related to the surgical navigation were discerned. Radical resection was achieved in 14 cases (70%). In five cases (25%), a tumor-positive resection margin (R1) was anticipated during surgery, as extensive radical resection was determined to be compromised. These patients all received intraoperative brachytherapy. In one case (5%), an unexpected R1 resection was performed. Surgical navigation during resection of LRRC is thus safe and feasible and enables accurate surgical guidance. MDPI 2022-04-27 /pmc/articles/PMC9143650/ /pubmed/35629313 http://dx.doi.org/10.3390/life12050645 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Groen, Harald C.
den Hartog, Anne G.
Heerink, Wouter J.
Kuhlmann, Koert F. D.
Kok, Niels F. M.
van Veen, Ruben
Hiep, Marijn A. J.
Snaebjornsson, Petur
Grotenhuis, Brechtje A.
Beets, Geerard L.
Aalbers, Arend G. J.
Ruers, Theo J. M.
Use of Image-Guided Surgical Navigation during Resection of Locally Recurrent Rectal Cancer
title Use of Image-Guided Surgical Navigation during Resection of Locally Recurrent Rectal Cancer
title_full Use of Image-Guided Surgical Navigation during Resection of Locally Recurrent Rectal Cancer
title_fullStr Use of Image-Guided Surgical Navigation during Resection of Locally Recurrent Rectal Cancer
title_full_unstemmed Use of Image-Guided Surgical Navigation during Resection of Locally Recurrent Rectal Cancer
title_short Use of Image-Guided Surgical Navigation during Resection of Locally Recurrent Rectal Cancer
title_sort use of image-guided surgical navigation during resection of locally recurrent rectal cancer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143650/
https://www.ncbi.nlm.nih.gov/pubmed/35629313
http://dx.doi.org/10.3390/life12050645
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