Association of a Common NOS1AP Variant with Attenuation of QTc Prolongation in Men with Heroin Dependence Undergoing Methadone Treatment †

Background: The effects of methadone-induced severe prolongation of the corrected QT interval (QTc) and sudden cardiac death appear unpredictable and sex-dependent. Genetic polymorphisms in the nitric oxide synthase 1 adaptor protein (NOS1AP) have been implicated in QTc prolongation in general popul...

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Detalles Bibliográficos
Autores principales: Chang, Kuan-Cheng, Chen, Ke-Wei, Huang, Chieh-Liang, Liao, Wen-Ling, Wu, Mei-Yao, Lin, Yu-Kai, Shiao, Yi-Tzone, Chung, Wei-Hsin, Lin, Yen-Nien, Lane, Hsien-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143734/
https://www.ncbi.nlm.nih.gov/pubmed/35629257
http://dx.doi.org/10.3390/jpm12050835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143734/
https://www.ncbi.nlm.nih.gov/pubmed/35629257
http://dx.doi.org/10.3390/jpm12050835

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