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Association of a Common NOS1AP Variant with Attenuation of QTc Prolongation in Men with Heroin Dependence Undergoing Methadone Treatment †
Background: The effects of methadone-induced severe prolongation of the corrected QT interval (QTc) and sudden cardiac death appear unpredictable and sex-dependent. Genetic polymorphisms in the nitric oxide synthase 1 adaptor protein (NOS1AP) have been implicated in QTc prolongation in general popul...
Autores principales: | Chang, Kuan-Cheng, Chen, Ke-Wei, Huang, Chieh-Liang, Liao, Wen-Ling, Wu, Mei-Yao, Lin, Yu-Kai, Shiao, Yi-Tzone, Chung, Wei-Hsin, Lin, Yen-Nien, Lane, Hsien-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143734/ https://www.ncbi.nlm.nih.gov/pubmed/35629257 http://dx.doi.org/10.3390/jpm12050835 |
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