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Micromanipulation and Automatic Data Analysis to Determine the Mechanical Strength of Microparticles

Microparticles are widely used in many industrial sectors. A micromanipulation technique has been widely used to quantify the mechanical properties of individual microparticles, which is crucial to the optimization of their functionality and performance in end-use applications. The principle of this...

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Autores principales: Zhang, Zhihua, He, Yanping, Zhang, Zhibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143736/
https://www.ncbi.nlm.nih.gov/pubmed/35630220
http://dx.doi.org/10.3390/mi13050751
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author Zhang, Zhihua
He, Yanping
Zhang, Zhibing
author_facet Zhang, Zhihua
He, Yanping
Zhang, Zhibing
author_sort Zhang, Zhihua
collection PubMed
description Microparticles are widely used in many industrial sectors. A micromanipulation technique has been widely used to quantify the mechanical properties of individual microparticles, which is crucial to the optimization of their functionality and performance in end-use applications. The principle of this technique is to compress single particles between two parallel surfaces, and the force versus displacement data are obtained simultaneously. Previously, analysis of the experimental data had to be done manually to calculate the rupture strength parameters of each individual particle, which is time-consuming. The aim of this study is to develop a software package that enables automatic analysis of the rupture strength parameters from the experimental data to enhance the capability of the micromanipulation technique. Three algorithms based on the combination of the “three-sigma rule”, a moving window, and the Hertz model were developed to locate the starting point where onset of compression occurs, and one algorithm based on the maximum deceleration was developed to identify the rupture point where a single particle is ruptured. Fifty microcapsules each with a liquid core and fifty porous polystyrene (PS) microspheres were tested in order to produce statistically representative results of each sample, and the experimental data were analysed using the developed software package. It is found that the results obtained from the combination of the “3σ + window” algorithm or the “3σ + window + Hertz” algorithm with the “maximum-deceleration” algorithm do not show any significant difference from the manual results. The data analysis time for each sample has been shortened from 2 to 3 h manually to within 20 min automatically.
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spelling pubmed-91437362022-05-29 Micromanipulation and Automatic Data Analysis to Determine the Mechanical Strength of Microparticles Zhang, Zhihua He, Yanping Zhang, Zhibing Micromachines (Basel) Article Microparticles are widely used in many industrial sectors. A micromanipulation technique has been widely used to quantify the mechanical properties of individual microparticles, which is crucial to the optimization of their functionality and performance in end-use applications. The principle of this technique is to compress single particles between two parallel surfaces, and the force versus displacement data are obtained simultaneously. Previously, analysis of the experimental data had to be done manually to calculate the rupture strength parameters of each individual particle, which is time-consuming. The aim of this study is to develop a software package that enables automatic analysis of the rupture strength parameters from the experimental data to enhance the capability of the micromanipulation technique. Three algorithms based on the combination of the “three-sigma rule”, a moving window, and the Hertz model were developed to locate the starting point where onset of compression occurs, and one algorithm based on the maximum deceleration was developed to identify the rupture point where a single particle is ruptured. Fifty microcapsules each with a liquid core and fifty porous polystyrene (PS) microspheres were tested in order to produce statistically representative results of each sample, and the experimental data were analysed using the developed software package. It is found that the results obtained from the combination of the “3σ + window” algorithm or the “3σ + window + Hertz” algorithm with the “maximum-deceleration” algorithm do not show any significant difference from the manual results. The data analysis time for each sample has been shortened from 2 to 3 h manually to within 20 min automatically. MDPI 2022-05-10 /pmc/articles/PMC9143736/ /pubmed/35630220 http://dx.doi.org/10.3390/mi13050751 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhang, Zhihua
He, Yanping
Zhang, Zhibing
Micromanipulation and Automatic Data Analysis to Determine the Mechanical Strength of Microparticles
title Micromanipulation and Automatic Data Analysis to Determine the Mechanical Strength of Microparticles
title_full Micromanipulation and Automatic Data Analysis to Determine the Mechanical Strength of Microparticles
title_fullStr Micromanipulation and Automatic Data Analysis to Determine the Mechanical Strength of Microparticles
title_full_unstemmed Micromanipulation and Automatic Data Analysis to Determine the Mechanical Strength of Microparticles
title_short Micromanipulation and Automatic Data Analysis to Determine the Mechanical Strength of Microparticles
title_sort micromanipulation and automatic data analysis to determine the mechanical strength of microparticles
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143736/
https://www.ncbi.nlm.nih.gov/pubmed/35630220
http://dx.doi.org/10.3390/mi13050751
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